S2544_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S2544_HUMAN
• UniProt AC: Q96H78
• Protein Name: Solute carrier family 25 member 44
• Gene Name: SLC25A44
• Organism: Homo sapiens (Human).
• Sequence Length: 314
• Subcellular Localization: Mitochondrion inner membrane; Multi-pass membrane protein.
• Protein Sequence: MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
183	Phosphorylation	ADGLRGFYRGYVASL HCCCCHHHHHHHHHH	13.12	-
298	Phosphorylation	VIVVGYESLKKLSLR EEEECHHHHHHHCCC	36.68	-
303	Phosphorylation	YESLKKLSLRPELVD HHHHHHHCCCHHHHC	31.08	24719451
311	Phosphorylation	LRPELVDSRHW---- CCHHHHCCCCC----	20.68	24719451
319	Phosphorylation	RHW------------ CCC------------		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S2544_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S2544_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S2544_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IMDH2_HUMAN	IMPDH2	physical	26186194
LASP1_HUMAN	LASP1	physical	26186194
IMDH2_HUMAN	IMPDH2	physical	28514442
LASP1_HUMAN	LASP1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.