dbPTM

S2542_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	S2542_MOUSE
UniProt AC	Q8R0Y8
Protein Name	Mitochondrial coenzyme A transporter SLC25A42
Gene Name	Slc25a42
Organism	Mus musculus (Mouse).
Sequence Length	318
Subcellular Localization	Mitochondrion inner membrane Multi-pass membrane protein.
Protein Description	Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate..
Protein Sequence	MGNGVQEGSVRLREDAEAVLAGAVSSKRDHRQVLSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRLLYFTYLNEGFLSLWRGNSATMVRVIPYAAIQFSAHEEYKRILGHYYGFRGEALPPWPRLLAGALAGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYFGFTPTVLGVIPYAGLSFFTYESLKSLHREYSGRPQPYPFERMVFGACAGLIGQSASYPLDVVRRRMQTAGVTGHQHGSILSTLRSIVREEGAVRGLYKGLSMNWLKGPIAVGISFTTFDLMQILLRRLQS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
66	Acetylation	IIFQVSSKRFSAKEA EEEEEECCCCCHHHH	50.37	23576753
235	S-nitrosocysteine	ERMVFGACAGLIGQS HHHHHHHHHHHHHHC	2.94	-
235	S-nitrosylation	ERMVFGACAGLIGQS HHHHHHHHHHHHHHC	2.94	21278135
256	Phosphorylation	VVRRRMQTAGVTGHQ HHHHHHHHCCCCCCC	18.94	22871156
269	Phosphorylation	HQHGSILSTLRSIVR CCCHHHHHHHHHHHH	24.59	22871156

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of S2542_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of S2542_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of S2542_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of S2542_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of S2542_MOUSE

Related Literatures of Post-Translational Modification