S2540_HUMAN - dbPTM
S2540_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID S2540_HUMAN
UniProt AC Q8TBP6
Protein Name Solute carrier family 25 member 40
Gene Name SLC25A40
Organism Homo sapiens (Human).
Sequence Length 338
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein.
Protein Description
Protein Sequence MDPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRRQQY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
52UbiquitinationAQNNPLPKGKCFVYS
CCCCCCCCCCEEEEC
77.8829967540
135UbiquitinationLSALLRSKLGENETC
HHHHHHHHCCCCCCH
54.82-
194PhosphorylationVSEDGWISLWRGWAP
CCCCCCEEEECCCCC
18.5124719451
234PhosphorylationKSGLYEPTFMINFTS
HCCCCCCEEEEEECC
17.56-
240PhosphorylationPTFMINFTSGALSGS
CEEEEEECCCCCCCC
23.05-
265PhosphorylationVVKTQKQTQLWTYES
EECCCCCEEEEEEEC
32.4427461979
269PhosphorylationQKQTQLWTYESHKIS
CCCEEEEEEECCCCC
26.4627461979
270PhosphorylationKQTQLWTYESHKISM
CCEEEEEEECCCCCC
12.1227461979
272PhosphorylationTQLWTYESHKISMPL
EEEEEEECCCCCCCC
21.4827461979
276PhosphorylationTYESHKISMPLHMST
EEECCCCCCCCHHHH
21.1024043423
282PhosphorylationISMPLHMSTWIIMKN
CCCCCHHHHHHHHHH
15.1624043423
283PhosphorylationSMPLHMSTWIIMKNI
CCCCHHHHHHHHHHH
17.0724043423
330UbiquitinationFGKAFFQKQNVRRQQ
HHHHHHHHHCCCCCC
38.39-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of S2540_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of S2540_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of S2540_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of S2540_HUMAN !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of S2540_HUMAN

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Related Literatures of Post-Translational Modification

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