| UniProt ID | S2539_HUMAN | |
|---|---|---|
| UniProt AC | Q9BZJ4 | |
| Protein Name | Solute carrier family 25 member 39 | |
| Gene Name | SLC25A39 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 359 | |
| Subcellular Localization |
Mitochondrion inner membrane Multi-pass membrane protein . |
|
| Protein Description | Required for normal heme biosynthesis.. | |
| Protein Sequence | MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 10 | Phosphorylation | DQDPAGISPLQQMVA CCCCCCCCHHHHHHH | 20.74 | 22210691 | |
| 41 | Phosphorylation | VVKVRLQSQRPSMAS HHHHHHHCCCCCHHH | 32.52 | 27762562 | |
| 45 | Phosphorylation | RLQSQRPSMASELMP HHHCCCCCHHHHHCC | 29.21 | 28387310 | |
| 48 | Phosphorylation | SQRPSMASELMPSSR CCCCCHHHHHCCCCC | 23.71 | 28674151 | |
| 134 | Phosphorylation | LPATLVMTVPATAIY CCCEEEEECCCEEEE | 18.83 | 29083192 | |
| 138 | Phosphorylation | LVMTVPATAIYFTAY EEEECCCEEEEEEHH | 13.91 | 29083192 | |
| 141 | Phosphorylation | TVPATAIYFTAYDQL ECCCEEEEEEHHHHH | 7.75 | 29083192 | |
| 143 | Phosphorylation | PATAIYFTAYDQLKA CCEEEEEEHHHHHHH | 13.82 | 29083192 | |
| 145 | Phosphorylation | TAIYFTAYDQLKAFL EEEEEEHHHHHHHHH | 10.93 | 29083192 | |
| 177 | Phosphorylation | LARLGTVTVISPLEL HHHCCCEEEECHHHH | 16.38 | 24719451 | |
| 180 (in isoform 2) | Ubiquitination | - | 21.06 | 21906983 | |
| 188 (in isoform 1) | Ubiquitination | - | 28.39 | 21906983 | |
| 188 | Ubiquitination | PLELMRTKLQAQHVS HHHHHHHHHHHCCCC | 28.39 | 21906983 | |
| 258 | Phosphorylation | DQTSVGMSFVAGGIS CCCCCCCEEECCCCC | 15.61 | 22210691 | |
| 267 | Phosphorylation | VAGGISGTVAAVLTL ECCCCCCCEEEEEEC | 10.53 | 22210691 | |
| 273 | Phosphorylation | GTVAAVLTLPFDVVK CCEEEEEECCHHHHH | 26.28 | - | |
| 333 | Phosphorylation | RIIKAAPSCAIMIST HHHHHCCCEEEEEEE | 16.08 | - | |
| 339 | Phosphorylation | PSCAIMISTYEFGKS CCEEEEEEEHHHHHH | 13.93 | - | |
| 340 | Phosphorylation | SCAIMISTYEFGKSF CEEEEEEEHHHHHHH | 19.02 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of S2539_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of S2539_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of S2539_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of S2539_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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