dbPTM

S22AN_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	S22AN_RAT
UniProt AC	Q9QZG1
Protein Name	Solute carrier family 22 member 23
Gene Name	Slc22a23
Organism	Rattus norvegicus (Rat).
Sequence Length	689
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MAIDRRREAAGSGAGRQPAPAEENGSLPPGDAAASAPLGGRAGSGGSAEIQPLPALHPSGGPHSSCCAAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCHGAGKGTELAGATVTGRWGDMGNWTSPSATPFSTASWGTTSNRSNSSDTPPLPSPPGKGNNDSNCECHAWDYGIRTGLVQNVVSKWDLVCDNAWKVHVAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSVIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLILYLTQKNCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIALASCLAMCLVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENIANGEHYTRQPLLSHKKGEQPLLLTNAELKDYSGLHDVAAVGDGLSEGATANGMKTM

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	RRREAAGSGAGRQPA HHHHHCCCCCCCCCC	22.27	25575281
24	N-linked_Glycosylation	QPAPAEENGSLPPGD CCCCCCCCCCCCCCC	36.54	-
26	Phosphorylation	APAEENGSLPPGDAA CCCCCCCCCCCCCHH	49.65	25575281
274	N-linked_Glycosylation	LTVALSVNVTMFSTL HHHHHHCCHHHHHHH	21.84	-
649	Ubiquitination	QPLLSHKKGEQPLLL CCCCCCCCCCCCEEE	63.36	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of S22AN_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of S22AN_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of S22AN_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of S22AN_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of S22AN_RAT

Related Literatures of Post-Translational Modification