S1PBP_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S1PBP_HUMAN
• UniProt AC: Q96BU1
• Protein Name: S100P-binding protein
• Gene Name: S100PBP {ECO:0000312|EMBL:AAH15175.1}
• Organism: Homo sapiens (Human).
• Sequence Length: 408
• Subcellular Localization: Nucleus . Colocalizes with S100P in the nucleus.
• Protein Sequence: MMCSRVPSEQSSGTSLLPKDGAPFSWDSLDEDGLDDSLLELSEGEEDDGDVNYTEEEIDALLKEDDPSYEQSSGEDDGGHVEKGERGSQILLDTPREKNSSYSLGPVAETPDLFKLPQLSTSSGHGPAHTKPLNRRSVLEKNLIKVTVAPFNPTVCDALLDKDETDSSKDTEKLSSLGEEMREDGLSPNESKLCTESEGISPNNSAWNGPQLSSSNNNFQQTVSDKNMPDSENPTSVFSRISDHSETPNMELSCRNGGSHKSSCEMRSLVVSTSSNKQDVLNKDSGKMKGHERRLGKVIPVLQTKTRTNVPTFSQSNLEQQKQLYLRSVIAHIEDPEDTNQGISGELCALMDQVHHMQHSKWQHPSDLTTRNYARRQKHLQRYSLTQWVDRNMRSHHRFQRLPDFSYS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MMCSRVPSEQSSGTS CCCCCCCCCCCCCCC	45.47	-
15	Phosphorylation	SEQSSGTSLLPKDGA CCCCCCCCCCCCCCC	31.28	24719451
69	Phosphorylation	LKEDDPSYEQSSGED HHCCCCCCCCCCCCC	24.31	23186163
72	Phosphorylation	DDPSYEQSSGEDDGG CCCCCCCCCCCCCCC	28.50	28985074
73	Phosphorylation	DPSYEQSSGEDDGGH CCCCCCCCCCCCCCC	45.99	28985074
88	Phosphorylation	VEKGERGSQILLDTP CCCCCCCCEEEECCC	21.92	-
94	Phosphorylation	GSQILLDTPREKNSS CCEEEECCCCCCCCC	24.98	21815630
100	Phosphorylation	DTPREKNSSYSLGPV CCCCCCCCCCCCCCC	41.54	21712546
101	Phosphorylation	TPREKNSSYSLGPVA CCCCCCCCCCCCCCC	28.30	25627689
102	Phosphorylation	PREKNSSYSLGPVAE CCCCCCCCCCCCCCC	14.03	21712546
122	Phosphorylation	KLPQLSTSSGHGPAH CCCCCCCCCCCCCCC	30.83	19413330
123	Phosphorylation	LPQLSTSSGHGPAHT CCCCCCCCCCCCCCC	34.59	19413330
130	Phosphorylation	SGHGPAHTKPLNRRS CCCCCCCCCCCCCHH	36.14	19413330
141	Ubiquitination	NRRSVLEKNLIKVTV CCHHHHHHCEEEEEE	53.55	-
176	Phosphorylation	KDTEKLSSLGEEMRE CHHHHHHHHHHHHHH	51.32	23186163
187	Phosphorylation	EMREDGLSPNESKLC HHHHCCCCCCHHHCC	31.07	25849741
191	Phosphorylation	DGLSPNESKLCTESE CCCCCCHHHCCCCCC	37.25	30108239
195	Phosphorylation	PNESKLCTESEGISP CCHHHCCCCCCCCCC	53.64	25627689
201	Phosphorylation	CTESEGISPNNSAWN CCCCCCCCCCCCCCC	32.22	25627689
205	Phosphorylation	EGISPNNSAWNGPQL CCCCCCCCCCCCCCC	41.10	25627689
213	Phosphorylation	AWNGPQLSSSNNNFQ CCCCCCCCCCCCCHH	26.86	28348404
214	Phosphorylation	WNGPQLSSSNNNFQQ CCCCCCCCCCCCHHH	45.75	28348404
215	Phosphorylation	NGPQLSSSNNNFQQT CCCCCCCCCCCHHHH	39.95	28348404
272	Phosphorylation	EMRSLVVSTSSNKQD EEEEEEEECCCCCCC	18.32	30576142
273	Phosphorylation	MRSLVVSTSSNKQDV EEEEEEECCCCCCCC	25.27	30576142
297	Ubiquitination	GHERRLGKVIPVLQT CCHHHHHCHHHEEEC	41.40	-
305	Ubiquitination	VIPVLQTKTRTNVPT HHHEEECCCCCCCCC	24.05	-
309	N-linked_Glycosylation	LQTKTRTNVPTFSQS EECCCCCCCCCCCHH	34.18	19349973
309	N-linked_Glycosylation	LQTKTRTNVPTFSQS EECCCCCCCCCCCHH	34.18	-
322	Ubiquitination	QSNLEQQKQLYLRSV HHHHHHHHHHHHHHH	41.80	21890473
322 (in isoform 1)	Ubiquitination	-	41.80	21890473
322 (in isoform 2)	Ubiquitination	-	41.80	21890473
383	Phosphorylation	RQKHLQRYSLTQWVD HHHHHHHHCHHHHHH	8.62	29209046
384	Phosphorylation	QKHLQRYSLTQWVDR HHHHHHHCHHHHHHH	27.42	29209046
386	Phosphorylation	HLQRYSLTQWVDRNM HHHHHCHHHHHHHHH	17.91	29209046

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S1PBP_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S1PBP_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S1PBP_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of S1PBP_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.