S18B1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S18B1_HUMAN
• UniProt AC: Q6NT16
• Protein Name: MFS-type transporter SLC18B1
• Gene Name: SLC18B1
• Organism: Homo sapiens (Human).
• Sequence Length: 456
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MEALGDLEGPRAPGGDDPAGSAGETPGWLSREQVFVLISAASVNLGSMMCYSILGPFFPKEAEKKGASNTIIGMIFGCFALFELLASLVFGNYLVHIGAKFMFVAGMFVSGGVTILFGVLDRVPDGPVFIAMCFLVRVMDAVSFAAAMTASSSILAKAFPNNVATVLGSLETFSGLGLILGPPVGGFLYQSFGYEVPFIVLGCVVLLMVPLNMYILPNYESDPGEHSFWKLIALPKVGLIAFVINSLSSCFGFLDPTLSLFVLEKFNLPAGYVGLVFLGMALSYAISSPLFGLLSDKRPPLRKWLLVFGNLITAGCYMLLGPVPILHIKSQLWLLVLILVVSGLSAGMSIIPTFPEILSCAHENGFEEGLSTLGLVSGLFSAMWSIGAFMGPTLGGFLYEKIGFEWAAAIQGLWALISGLAMGLFYLLEYSRRKRSKSQNILSTEEERTTLLPNET

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MEALGDLE -------CCCCCCCC	6.49	22814378
21	Phosphorylation	GGDDPAGSAGETPGW CCCCCCCCCCCCCCC	34.90	23917254
39	Phosphorylation	EQVFVLISAASVNLG HHHHHHHEHHCCCHH	17.39	22210691
42	Phosphorylation	FVLISAASVNLGSMM HHHHEHHCCCHHHHH	15.97	22210691
47	Phosphorylation	AASVNLGSMMCYSIL HHCCCHHHHHHHHHH	13.40	22210691
51	Phosphorylation	NLGSMMCYSILGPFF CHHHHHHHHHHCCCC	4.85	22210691
52	Phosphorylation	LGSMMCYSILGPFFP HHHHHHHHHHCCCCC	13.35	22210691
143	Phosphorylation	VRVMDAVSFAAAMTA HHHHHHHHHHHHHHH	15.76	-
426	Phosphorylation	GLAMGLFYLLEYSRR HHHHHHHHHHHHHHH	18.54	-
430	Phosphorylation	GLFYLLEYSRRKRSK HHHHHHHHHHHCCCC	13.88	-
436	Phosphorylation	EYSRRKRSKSQNILS HHHHHCCCCCCCCCC	39.43	30108239
437	Ubiquitination	YSRRKRSKSQNILST HHHHCCCCCCCCCCC	61.16	21906983
438	Phosphorylation	SRRKRSKSQNILSTE HHHCCCCCCCCCCCH	29.70	25159151
443	Phosphorylation	SKSQNILSTEEERTT CCCCCCCCCHHHHHC	29.94	23312004
444	Phosphorylation	KSQNILSTEEERTTL CCCCCCCCHHHHHCC	43.93	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S18B1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S18B1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S18B1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of S18B1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.