S14L5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S14L5_HUMAN
• UniProt AC: O43304
• Protein Name: SEC14-like protein 5
• Gene Name: SEC14L5
• Organism: Homo sapiens (Human).
• Sequence Length: 696
• Protein Sequence: MVQRYQSPVRVYKYPFELVMAAYEKRFPTCPQIPVFLGSEVLRESRSPDGAVHVVERSCRLRVDAPRLLRKIAGVEHVVFVQTNILNWKERTLLIEAHNETFANRVVVNEHCSYTVHPENEDWTCFEQSASLDIRSFFGFENALEKIAMKQYTANVKRGKEVIEHYLNELISQGTSHIPRWTPAPVREEDARNQAGPRDPSSLEAHGPRSTLGPALEAVSMDGDKLDADYIERCLGHLTPMQESCLIQLRHWLQETHKGKIPKDEHILRFLRAHDFHLDKAREMLRQSLSWRKQHQVDLLLQTWQPPALLEEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVGEEALLRHVLSVNEEGQKRCEGSTRQLGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLISPFINENTRRKFLIYSGSNYQGPGGLVDYLDREVIPDFLGGESVCNVPEGGLVPKSLYMTEEEQEHTDQLWQWSETYHSASVLRGAPHEVAVEILEGESVITWDFDILRGDVVFSLYHTKQAPRLGAREPGTRASGQLIDKGWVLGRDYSRVEAPLVCREGESIQGSHVTRWPGVYLLQWQMHSPPSSVACSLPGVDDVLTALHSPGPKCKLLYYCEVLASEDFRGSMSSLESCTSGFSQLSAATSSSSSGQSHSSSLVSR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	FELVMAAYEKRFPTC HHHHHHHHHHHCCCC	16.67	-
152	Phosphorylation	EKIAMKQYTANVKRG HHHHHHHHHCCCCCH	11.42	30278072
153	Phosphorylation	KIAMKQYTANVKRGK HHHHHHHHCCCCCHH	14.84	23532336
201	Phosphorylation	QAGPRDPSSLEAHGP CCCCCCHHHHHHCCC	52.42	28270605
202	Phosphorylation	AGPRDPSSLEAHGPR CCCCCHHHHHHCCCC	35.30	28060719
220	Phosphorylation	GPALEAVSMDGDKLD CHHHHEECCCCCCCC	20.43	28060719
230	Phosphorylation	GDKLDADYIERCLGH CCCCCHHHHHHHHHC	13.35	28796482
263	Ubiquitination	THKGKIPKDEHILRF HCCCCCCCHHHHHHH	78.28	-
290	Phosphorylation	EMLRQSLSWRKQHQV HHHHHHHHHHHHHHH	30.04	24719451
412	Phosphorylation	IEVVEDNYPETLGRL HHHHHHCCCHHHCHH	18.11	-
455	Phosphorylation	LIYSGSNYQGPGGLV EEECCCCCCCCCCHH	19.28	-
464	Phosphorylation	GPGGLVDYLDREVIP CCCCHHHHCCCCCCC	11.74	-
554	Phosphorylation	VVFSLYHTKQAPRLG EEEEEEECCCCCCCC	15.99	28555341
674	Phosphorylation	ESCTSGFSQLSAATS HHHCCCHHHHHCCCC	33.46	-
688	Phosphorylation	SSSSSGQSHSSSLVS CCCCCCCCCCCCCCC	28.94	-
695	Phosphorylation	SHSSSLVSR------ CCCCCCCCC------	37.25	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S14L5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S14L5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S14L5_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of S14L5_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.