| UniProt ID | S10A6_MOUSE | |
|---|---|---|
| UniProt AC | P14069 | |
| Protein Name | Protein S100-A6 | |
| Gene Name | S100a6 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 89 | |
| Subcellular Localization |
Nucleus envelope. Cytoplasm. Cell membrane Peripheral membrane protein Cytoplasmic side. |
|
| Protein Description | May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative (By similarity).. | |
| Protein Sequence | MACPLDQAIGLLVAIFHKYSGKEGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMDDLDRNKDQEVNFQEYVAFLGALALIYNEALK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 19 | Phosphorylation | LVAIFHKYSGKEGDK HHHHHHHHCCCCCCC | 17.68 | 25367039 | |
| 20 | Phosphorylation | VAIFHKYSGKEGDKH HHHHHHHCCCCCCCC | 48.47 | 25367039 | |
| 22 | Acetylation | IFHKYSGKEGDKHTL HHHHHCCCCCCCCCC | 53.21 | 22826441 | |
| 26 | Acetylation | YSGKEGDKHTLSKKE HCCCCCCCCCCCHHH | 49.71 | 22826441 | |
| 32 | Acetylation | DKHTLSKKELKELIQ CCCCCCHHHHHHHHH | 65.97 | 19849973 | |
| 35 | Acetylation | TLSKKELKELIQKEL CCCHHHHHHHHHHHC | 52.12 | 23236377 | |
| 40 | Acetylation | ELKELIQKELTIGSK HHHHHHHHHCCCCHH | 47.93 | 22826441 | |
| 43 | Phosphorylation | ELIQKELTIGSKLQD HHHHHHCCCCHHHCH | 25.12 | 29514104 | |
| 46 | Phosphorylation | QKELTIGSKLQDAEI HHHCCCCHHHCHHHH | 26.75 | 28507225 | |
| 47 | Acetylation | KELTIGSKLQDAEIA HHCCCCHHHCHHHHH | 44.98 | 23806337 | |
| 47 | Succinylation | KELTIGSKLQDAEIA HHCCCCHHHCHHHHH | 44.98 | - | |
| 47 | Ubiquitination | KELTIGSKLQDAEIA HHCCCCHHHCHHHHH | 44.98 | - | |
| 47 | Succinylation | KELTIGSKLQDAEIA HHCCCCHHHCHHHHH | 44.98 | 23806337 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of S10A6_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of S10A6_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of S10A6_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of S10A6_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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