S10A4_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S10A4_MOUSE
• UniProt AC: P07091
• Protein Name: Protein S100-A4
• Gene Name: S100a4
• Organism: Mus musculus (Mouse).
• Sequence Length: 101
• Protein Sequence: MARPLEEALDVIVSTFHKYSGKEGDKFKLNKTELKELLTRELPSFLGKRTDEAAFQKVMSNLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGCPDKEPRKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MARPLEEAL ------CCCCHHHHH	23.07	-
14	Phosphorylation	EALDVIVSTFHKYSG HHHHHHHHHHHHHCC	17.77	25338131
18	Acetylation	VIVSTFHKYSGKEGD HHHHHHHHHCCCCCC	36.60	23236377
22	Acetylation	TFHKYSGKEGDKFKL HHHHHCCCCCCCCCC	53.21	22826441
26	Acetylation	YSGKEGDKFKLNKTE HCCCCCCCCCCCHHH	56.08	22826441
31	Acetylation	GDKFKLNKTELKELL CCCCCCCHHHHHHHH	54.54	22826441
32	Phosphorylation	DKFKLNKTELKELLT CCCCCCHHHHHHHHH	45.54	29176673
35	Acetylation	KLNKTELKELLTREL CCCHHHHHHHHHHHC	39.83	23236377
35	Ubiquitination	KLNKTELKELLTREL CCCHHHHHHHHHHHC	39.83	-
44	Phosphorylation	LLTRELPSFLGKRTD HHHHHCHHHHCCCCC	45.81	24899341
48	Acetylation	ELPSFLGKRTDEAAF HCHHHHCCCCCHHHH	55.03	22826441
50	Phosphorylation	PSFLGKRTDEAAFQK HHHHCCCCCHHHHHH	41.50	24899341
57	Ubiquitination	TDEAAFQKVMSNLDS CCHHHHHHHHHCCCC	33.19	-
57	Acetylation	TDEAAFQKVMSNLDS CCHHHHHHHHHCCCC	33.19	23236377
60	Phosphorylation	AAFQKVMSNLDSNRD HHHHHHHHCCCCCCC	36.91	24899341
64	Phosphorylation	KVMSNLDSNRDNEVD HHHHCCCCCCCCCCC	36.61	24899341

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S10A4_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S10A4_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S10A4_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MAP2_MOUSE	Metap2	physical	11994292

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.