| UniProt ID | RUSD1_HUMAN | |
|---|---|---|
| UniProt AC | Q9UJJ7 | |
| Protein Name | RNA pseudouridylate synthase domain-containing protein 1 | |
| Gene Name | RPUSD1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 312 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MEPGSVENLSIVYRSRDFLVVNKHWDVRIDSKAWRETLTLQKQLRYRFPELADPDTCYGFRFCHQLDFSTSGALCVALNKAAAGSAYRCFKERRVTKAYLALLRGHIQESRVTISHAIGRNSTEGRAHTMCIEGSQGCENPKPSLTDLVVLEHGLYAGDPVSKVLLKPLTGRTHQLRVHCSALGHPVVGDLTYGEVSGREDRPFRMMLHAFYLRIPTDTECVEVCTPDPFLPSLDACWSPHTLLQSLDQLVQALRATPDPDPEDRGPRPGSPSALLPGPGRPPPPPTKPPETEAQRGPCLQWLSEWTLEPDS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MEPGSVEN -------CCCCCEEC | 14.66 | 22814378 | |
| 5 | Phosphorylation | ---MEPGSVENLSIV ---CCCCCEECEEEE | 36.65 | 27732954 | |
| 10 | Phosphorylation | PGSVENLSIVYRSRD CCCEECEEEEEECCC | 22.91 | 27732954 | |
| 13 | Phosphorylation | VENLSIVYRSRDFLV EECEEEEEECCCEEE | 10.95 | 29759185 | |
| 15 | Phosphorylation | NLSIVYRSRDFLVVN CEEEEEECCCEEEEE | 20.65 | - | |
| 32 | Ubiquitination | WDVRIDSKAWRETLT CCEEECCHHHHHHHH | 48.50 | - | |
| 42 | Ubiquitination | RETLTLQKQLRYRFP HHHHHHHHHHHHHCH | 55.18 | - | |
| 97 | Ubiquitination | FKERRVTKAYLALLR HHHHHHHHHHHHHHH | 31.98 | - | |
| 99 | Phosphorylation | ERRVTKAYLALLRGH HHHHHHHHHHHHHHH | 8.28 | 20393185 | |
| 122 | Phosphorylation | SHAIGRNSTEGRAHT EECCCCCCCCCCCEE | 26.86 | 28555341 | |
| 167 | Ubiquitination | PVSKVLLKPLTGRTH CHHHHEEEECCCCCE | 33.54 | 2190698 | |
| 193 | Phosphorylation | PVVGDLTYGEVSGRE CEEECCCCCCCCCCC | 20.70 | 27642862 | |
| 257 | Phosphorylation | LVQALRATPDPDPED HHHHHHCCCCCCHHH | 23.07 | 28464451 | |
| 271 | Phosphorylation | DRGPRPGSPSALLPG HCCCCCCCCCCCCCC | 20.54 | 28731282 | |
| 273 | Phosphorylation | GPRPGSPSALLPGPG CCCCCCCCCCCCCCC | 32.99 | 28464451 | |
| 287 | Phosphorylation | GRPPPPPTKPPETEA CCCCCCCCCCCCCCH | 63.05 | 23312004 | |
| 292 | Phosphorylation | PPTKPPETEAQRGPC CCCCCCCCCHHCCCC | 42.25 | 23186163 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RUSD1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RUSD1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RUSD1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of RUSD1_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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