| UniProt ID | RUFY2_MOUSE | |
|---|---|---|
| UniProt AC | Q8R4C2 | |
| Protein Name | RUN and FYVE domain-containing protein 2 | |
| Gene Name | Rufy2 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 606 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | ||
| Protein Sequence | MATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKGRKSFLSYNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRELLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEEIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENELILMRTRQHLEVTKVDVETELQTYKHSRQGLDEMYNDARRQLRDESQLRQDVENELSVQVGMKHEMELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQRLQGSEDGLKEKNEIIARLEEKTNKITTAMRQLEQRLQQAEKAQKEAEAEDEKYAQECLSQSDSLQRQISQKEQQLVQLETDLKIEKEWRQTLQEDLQKEKDVLSHLRHETQKVISLKKEFLNLQDENQQLKRIYQEQEQALQELGSKLCESKLKIDDIKEANKALQGLVWLKDKDATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHAMLIQRCSSNMP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 63 | Phosphorylation | HGLKGRKSFLSYNKT CCCCCCHHHHCCCCC | 30.02 | 25338131 | |
| 99 | Ubiquitination | VRDLPGLKTPLGRAR HHHCCCCCCHHHHHH | 54.75 | - | |
| 269 | Phosphorylation | NELILMRTRQHLEVT HHHHHHHHHHCCEEE | 22.25 | 26824392 | |
| 276 | Phosphorylation | TRQHLEVTKVDVETE HHHCCEEEEEEHHHH | 18.90 | 26824392 | |
| 287 | Phosphorylation | VETELQTYKHSRQGL HHHHHHHHHHHHHCH | 8.17 | - | |
| 298 | Phosphorylation | RQGLDEMYNDARRQL HHCHHHHHHHHHHHH | 14.08 | - | |
| 338 | Ubiquitination | LAMKLLEKDIHEKQD HHHHHHHHHHHHHHH | 63.05 | - | |
| 389 | Phosphorylation | IARLEEKTNKITTAM HHHHHHHHHHHHHHH | 45.05 | 20469934 | |
| 393 | Phosphorylation | EEKTNKITTAMRQLE HHHHHHHHHHHHHHH | 15.31 | 20469934 | |
| 394 | Phosphorylation | EKTNKITTAMRQLEQ HHHHHHHHHHHHHHH | 23.17 | 20469934 | |
| 430 | Phosphorylation | ECLSQSDSLQRQISQ HHHHCCHHHHHHHHH | 31.48 | 23608596 | |
| 436 | Phosphorylation | DSLQRQISQKEQQLV HHHHHHHHHHHHHHH | 27.19 | 29514104 | |
| 458 | Phosphorylation | IEKEWRQTLQEDLQK HHHHHHHHHHHHHHH | 23.10 | 19367708 | |
| 482 | Phosphorylation | HETQKVISLKKEFLN HHHHHHHHHHHHHHC | 36.80 | 24719451 | |
| 518 | Phosphorylation | LGSKLCESKLKIDDI HHHHHHHHCCCHHHH | 42.14 | - | |
| 574 | Phosphorylation | EIFCNACSDNELPLP CEECCCCCCCCCCCC | 40.85 | 25777480 | |
| 582 | Phosphorylation | DNELPLPSSPKPVRV CCCCCCCCCCCCEEE | 67.94 | 23984901 | |
| 583 | Phosphorylation | NELPLPSSPKPVRVC CCCCCCCCCCCEEEC | 34.70 | 23984901 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RUFY2_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RUFY2_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RUFY2_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of RUFY2_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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