dbPTM

RTOR1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RTOR1_ARATH
UniProt AC	Q93YQ1
Protein Name	Regulatory-associated protein of TOR 1
Gene Name	RAPTOR1
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	1344
Subcellular Localization
Protein Description	Probable component of the plant TOR kinase pathway that recruits substrates for TOR. Modulates plant cell growth and regulates the activity of ATPK1 kinase in response to osmotic stress..
Protein Sequence	MALGDLMVSRFSQSSVSLVSNHRYDEDCVSSHDDGDSRRKDSEAKSSSSYGNGTTEGAATATSMAYLPQTIVLCELRHDASEASAPLGTSEIVLVPKWRLKERMKTGCVALVLCLNITVDPPDVIKISPCARIEAWIDPFSMAPPKALETIGKNLSTQYERWQPRARYKVQLDPTVDEVRKLCLTCRKYAKTERVLFHYNGHGVPKPTANGEIWVFNKSYTQYIPLPISELDSWLKTPSIYVFDCSAARMILNAFAELHDWGSSGSSGSSRDCILLAACDVHETLPQSVEFPADVFTSCLTTPIKMALKWFCRRSLLKEIIDESLIDRIPGRQNDRKTLLGELNWIFTAVTDTIAWNVLPHELFQRLFRQDLLVASLFRNFLLAERIMRSANCNPISHPMLPPTHQHHMWDAWDMAAEICLSQLPQLVLDPSTEFQPSPFFTEQLTAFEVWLDHGSEHKKPPEQLPIVLQVLLSQCHRFRALVLLGRFLDMGSWAVDLALSVGIFPYVLKLLQTTTNELRQILVFIWTKILALDKSCQIDLVKDGGHTYFIRFLDSSGAFPEQRAMAAFVLAVIVDGHRRGQEACLEANLIGVCLGHLEASRPSDPQPEPLFLQWLCLCLGKLWEDFMEAQIMGREANAFEKLAPLLSEPQPEVRAAAVFALGTLLDIGFDSNKSVVEDEFDDDEKIRAEDAIIKSLLDVVSDGSPLVRAEVAVALARFAFGHKQHLKLAAASYWKPQSSSLLTSLPSIAKFHDPGSATIVSLHMSPLTRASTDSQPVARESRISSSPLGSSGLMQGSPLSDDSSLHSDSGMMHDSVSNGAVHQPRLLDNAVYSQCVRAMFALAKDPSPRIASLGRRVLSIIGIEQVVAKPSKPTGRPGEAATTSHTPLAGLARSSSWFDMHAGNLPLSFRTPPVSPPRTNYLSGLRRVCSLEFRPHLLGSPDSGLADPLLGASGSERSLLPLSTIYGWSCGHFSKPLLGGADASQEIAAKREEKEKFALEHIAKCQHSSISKLNNNPIANWDTRFETGTKTALLHPFSPIVVAADENERIRVWNYEEATLLNGFDNHDFPDKGISKLCLINELDDSLLLVASCDGSVRIWKNYATKGKQKLVTGFSSIQGHKPGARDLNAVVDWQQQSGYLYASGETSTVTLWDLEKEQLVRSVPSESECGVTALSASQVHGGQLAAGFADGSLRLYDVRSPEPLVCATRPHQKVERVVGLSFQPGLDPAKVVSASQAGDIQFLDLRTTRDTYLTIDAHRGSLTALAVHRHAPIIASGSAKQLIKVFSLQGEQLGIIRYYPSFMAQKIGSVSCLTFHPYQVLLAAGAADSFVSIYTHDNSQAR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	DLMVSRFSQSSVSLV HHHHHCCCCCCEEHH	28.22	25561503
14	Phosphorylation	MVSRFSQSSVSLVSN HHHCCCCCCEEHHCC	31.35	23111157
15	Phosphorylation	VSRFSQSSVSLVSNH HHCCCCCCEEHHCCC	14.21	25561503
17	Phosphorylation	RFSQSSVSLVSNHRY CCCCCCEEHHCCCCC	25.63	29654922
705	Phosphorylation	LDVVSDGSPLVRAEV HHHHCCCCHHHHHHH	21.76	19880383
739	Phosphorylation	ASYWKPQSSSLLTSL HHHCCCCCCCHHHCC	30.35	25561503
740	Phosphorylation	SYWKPQSSSLLTSLP HHCCCCCCCHHHCCC	21.54	25561503
744	Phosphorylation	PQSSSLLTSLPSIAK CCCCCHHHCCCCHHC	33.25	25561503
745	Phosphorylation	QSSSLLTSLPSIAKF CCCCHHHCCCCHHCC	37.95	25561503
748	Phosphorylation	SLLTSLPSIAKFHDP CHHHCCCCHHCCCCC	40.23	25561503
772	Phosphorylation	MSPLTRASTDSQPVA CCCCCCCCCCCCCCC	29.47	25561503
773	Phosphorylation	SPLTRASTDSQPVAR CCCCCCCCCCCCCCC	38.39	25561503
782	Phosphorylation	SQPVARESRISSSPL CCCCCCCCCCCCCCC	29.39	29654922
883	Phosphorylation	GRPGEAATTSHTPLA CCCCCCCCCCCCCCC	35.56	29654922
884	Phosphorylation	RPGEAATTSHTPLAG CCCCCCCCCCCCCCH	17.49	25561503
885	Phosphorylation	PGEAATTSHTPLAGL CCCCCCCCCCCCCHH	22.47	25561503
887	Phosphorylation	EAATTSHTPLAGLAR CCCCCCCCCCCHHCC	21.55	29654922
912	Phosphorylation	NLPLSFRTPPVSPPR CCCCCCCCCCCCCCC	29.90	23776212
916	Phosphorylation	SFRTPPVSPPRTNYL CCCCCCCCCCCCCCC	34.65	23776212
931	Phosphorylation	SGLRRVCSLEFRPHL CCCCHHHCCCCCHHH	28.25	30291188
941	Phosphorylation	FRPHLLGSPDSGLAD CCHHHCCCCCCCCCC	26.04	23111157
944	Phosphorylation	HLLGSPDSGLADPLL HHCCCCCCCCCCHHC	38.81	27643528
954	Phosphorylation	ADPLLGASGSERSLL CCHHCCCCCCCCCCC	40.84	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RTOR1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RTOR1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RTOR1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RTOR1_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-931, AND MASSSPECTROMETRY.	19376835 [Abstract]