RTNLE_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RTNLE_ARATH
• UniProt AC: O82352
• Protein Name: Reticulon-like protein B5
• Gene Name: RTNLB5
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 255
• Subcellular Localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
• Protein Sequence: MAEEIEKSVPTEESLMEKISEKIHHHDSSSSSESEYEKPDSPSAVKAKIYRMFGREKPVHKVLGGGKPADVFLWRDKKLSGAVLGVATAIWVLFELVEYHLLSLLCHISILALGGLFLWSNAHTLINKTSPQIPEIHVPEEAFLVVASSLRNELNQAFVILRSIALGRDLKKFLMVVVGLWIISVVGNWFNFLTLVYICFVILHTVPMLYEKHEDKVDPLAEKAMKELQKQYVVFDEKVLSKIPIASLKAKAKLG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAEEIEKSV ------CHHHHHHHC	24.11	22223895
28	Phosphorylation	EKIHHHDSSSSSESE HHHCCCCCCCCCCCC	27.97	15308754
29	Phosphorylation	KIHHHDSSSSSESEY HHCCCCCCCCCCCCC	40.05	15308754
30	Phosphorylation	IHHHDSSSSSESEYE HCCCCCCCCCCCCCC	41.66	15308754
31	Phosphorylation	HHHDSSSSSESEYEK CCCCCCCCCCCCCCC	39.82	15308754
32	Phosphorylation	HHDSSSSSESEYEKP CCCCCCCCCCCCCCC	47.27	15308754
34	Phosphorylation	DSSSSSESEYEKPDS CCCCCCCCCCCCCCC	47.64	15308754
36	Phosphorylation	SSSSESEYEKPDSPS CCCCCCCCCCCCCHH	38.23	23776212
41	Phosphorylation	SEYEKPDSPSAVKAK CCCCCCCCHHHHHHH	29.31	15308754
43	Phosphorylation	YEKPDSPSAVKAKIY CCCCCCHHHHHHHHH	50.04	15308754
247	Phosphorylation	LSKIPIASLKAKAKL HHCCCHHHHHHHHCC	30.99	17317660

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RTNLE_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RTNLE_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RTNLE_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of RTNLE_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteomics of the Arabidopsis plasma membrane and a newphosphorylation site database.";
Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.;
Plant Cell 16:2394-2405(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-28; SER-29; SER-30;SER-31 AND SER-32, AND MASS SPECTROMETRY.
PubMed: 15308754

"Large-scale analysis of in vivo phosphorylated membrane proteins byimmobilized metal ion affinity chromatography and mass spectrometry.";
Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.;
Mol. Cell. Proteomics 2:1234-1243(2003).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-28; SER-29; SER-30;SER-31; SER-32 AND SER-43, AND MASS SPECTROMETRY.
PubMed: 14506206