| UniProt ID | RTKN2_MOUSE | |
|---|---|---|
| UniProt AC | Q14B46 | |
| Protein Name | Rhotekin-2 | |
| Gene Name | Rtkn2 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 604 | |
| Subcellular Localization | ||
| Protein Description | May play an important role in lymphopoiesis.. | |
| Protein Sequence | MEGQLLRGLAAQQDCSIREKIDLEIRMREGIWKLLSLSTKKDQVLHAVKNLMVCSARIQAYTAELQKSKEEIANQTGARLVLDSSSENKEGESCRGKIALSDIRIPLMWKDSDHFSNKECTQRFAIFCLFRMGAQVFDTDMVIVDQTVTDICFENVTIFNEAGPDFQIKIEVYSCSAEESSLTNTPRKLAKKLKTSISKATGRKISAALQEESPEACLLAGSVAGAKYHLLAHTTLTLENAGDCFKTHNLSVHGDEECSFWLPLYGNVCCRLVAQPACMAADAFAGFLNEQQTGKGLVGWRRLYCALRGGKLRCFYGPEEIEAKVEPALVVPIDKETRIQAVEKDSKKMHCFSVLSTAAGRAVSHIFAADSLADFQEWMGAFRQHFFDLSQWKHCCEELMRIEIMSPRKPPLFLAKEATSVYYDMSIDSPVKLESVTDIIQKKIGETNRQFLIGRDDQSAAPPWAAVFDGNHEMVIEKKVLSPIGEPAPDGKRKKRRAPLPPTDQPPFCIKTQGRANQSKDSATQAGVSGASSSPSDPRLSPPTHHLQKPVAAPRKLLPARKNSSADIGHTDTKTSLDAKPVPVPRQKSIRDILDPRSWLQAQV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 36 | Phosphorylation | EGIWKLLSLSTKKDQ CCHHHHHHCCCCHHH | 30.61 | 24759943 | |
| 38 | Phosphorylation | IWKLLSLSTKKDQVL HHHHHHCCCCHHHHH | 34.50 | 24759943 | |
| 39 | Phosphorylation | WKLLSLSTKKDQVLH HHHHHCCCCHHHHHH | 47.62 | 24759943 | |
| 81 (in isoform 2) | Phosphorylation | - | 4.68 | 22871156 | |
| 195 | Phosphorylation | KLAKKLKTSISKATG HHHHHHHHHHHHHHC | 41.55 | 28066266 | |
| 196 | Phosphorylation | LAKKLKTSISKATGR HHHHHHHHHHHHHCC | 24.23 | 28066266 | |
| 198 | Phosphorylation | KKLKTSISKATGRKI HHHHHHHHHHHCCHH | 18.92 | 28066266 | |
| 206 | Phosphorylation | KATGRKISAALQEES HHHCCHHHHHHHHCC | 15.55 | 19060867 | |
| 213 | Phosphorylation | SAALQEESPEACLLA HHHHHHCCHHHHHHH | 27.56 | 21082442 | |
| 406 | Phosphorylation | LMRIEIMSPRKPPLF HHCCEECCCCCCCEE | 27.49 | 28066266 | |
| 541 | Phosphorylation | SPSDPRLSPPTHHLQ CCCCCCCCCCCCCCC | 30.07 | 28418008 | |
| 564 | Phosphorylation | LLPARKNSSADIGHT HCCCCCCCCCCCCCC | 29.91 | 26824392 | |
| 565 | Phosphorylation | LPARKNSSADIGHTD CCCCCCCCCCCCCCC | 39.08 | 28066266 | |
| 589 | Phosphorylation | VPVPRQKSIRDILDP CCCCCCCCHHHHCCH | 17.95 | 26643407 | |
| 598 | Phosphorylation | RDILDPRSWLQAQV- HHHCCHHHHHHHCC- | 37.21 | 26643407 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RTKN2_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RTKN2_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RTKN2_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of RTKN2_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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