RT27_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RT27_MOUSE
• UniProt AC: Q8BK72
• Protein Name: 28S ribosomal protein S27, mitochondrial {ECO:0000305}
• Gene Name: Mrps27 {ECO:0000312|MGI:MGI:1919064}
• Organism: Mus musculus (Mouse).
• Sequence Length: 415
• Subcellular Localization: Cytoplasm . Mitochondrion .
• Protein Description: RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues..
• Protein Sequence: MAAPMVRCGMLLARRLDASRLCLAGKRCLLSAAYVDSHQWEAREKEEYHLADLASLMDKAYERKLPVSSLSISRFVDNIASREDLDSAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKYGAQDKALYTLVNKVQYGIFPDNFTFNLLMDYFIKKGNYKDALSVVFEIMMQEAFDVPSTQFLSLYVLYRCLAEKTELTWEEERDFGASLLLSGLKQRNTVGLSSQLYGYALLGKVELQRGVRAVYHGMPLMWTPGYLDRALQVMERVASSPEDLKLGREVLDVLDGVLKVVTSPDVQTSEAQPQEGEDGLGSANLVEQLDTEEPEQSKLPRYLERFQASRSKLQELNRVESESLLTLTTQLVKEKLPACEAEDLATYEQKLREWHLERVQLIQREQEQREKAKQEYQALSAAEKAA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
71	Phosphorylation	KLPVSSLSISRFVDN CCCCCHHHHHHHHHH	22.07	-
90	Phosphorylation	EDLDSAEYYLYKFRH CCCCCCHHHHHHCCC	9.85	-
94	Acetylation	SAEYYLYKFRHSPNC CCHHHHHHCCCCCCC	33.07	23864654
94	Succinylation	SAEYYLYKFRHSPNC CCHHHHHHCCCCCCC	33.07	23954790
274	Acetylation	ASSPEDLKLGREVLD HCCHHHHHHHHHHHH	62.31	23954790
341	Acetylation	RFQASRSKLQELNRV HHHHHHHHHHHHHHH	53.75	23201123
362	Acetylation	TLTTQLVKEKLPACE HHHHHHHHHHCCCCC	58.69	23864654
364	Acetylation	TTQLVKEKLPACEAE HHHHHHHHCCCCCHH	54.79	23201123

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RT27_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RT27_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RT27_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RT27_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.