dbPTM

RSAD1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RSAD1_HUMAN
UniProt AC	Q9HA92
Protein Name	Radical S-adenosyl methionine domain-containing protein 1, mitochondrial
Gene Name	RSAD1
Organism	Homo sapiens (Human).
Sequence Length	442
Subcellular Localization	Mitochondrion .
Protein Description	May be involved in porphyrin cofactor biosynthesis..
Protein Sequence	MALPGARARGWAAAARAAQRRRRVENAGGSPSPEPAGRRAALYVHWPYCEKRCSYCNFNKYIPRRLEEAAMQKCLVTEAQTLLRLSGVQRVESVFFGGGTPSLASPHTVAAVLEAVAQAAHLPADLEVTLEANPTSAPGSRLAEFGAAGVNRLSIGLQSLDDTELRLLGRTHSACDALRTLAEARRLFPGRVSVDLMLGLPAQQVGPWLGQLQELLHHCDDHLSLYQLSLERGTALFAQVQRGALPAPDPELAAEMYQRGRAVLREAGFHQYEVSNFARNGALSTHNWTYWQCGQYLGVGPGAHGRFMPQGAGGHTREARIQTLEPDNWMKEVMLFGHGTRKRVPLGRLELLEEVLALGLRTDVGITHQHWQQFEPQLTLWDVFGANKEVQELLERGLLQLDHRGLRCSWEGLAVLDSLLLTLLPQLQEAWQQRTPSPVPGG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Methylation	ALPGARARGWAAAAR CCCCHHHHHHHHHHH	35.32	115492955
30	Phosphorylation	RVENAGGSPSPEPAG HHHHCCCCCCCCCCC	22.68	29255136
32	Phosphorylation	ENAGGSPSPEPAGRR HHCCCCCCCCCCCCC	43.52	29255136
60	Ubiquitination	CSYCNFNKYIPRRLE CCCCCCCHHCCHHHH	40.18	-
323	Phosphorylation	TREARIQTLEPDNWM CCEECEEEECCCCHH	30.62	24719451
331	Ubiquitination	LEPDNWMKEVMLFGH ECCCCHHHHHHHHCC	38.48	-
418	Phosphorylation	EGLAVLDSLLLTLLP HHHHHHHHHHHHHHH	19.43	26074081
422	Phosphorylation	VLDSLLLTLLPQLQE HHHHHHHHHHHHHHH	26.64	26074081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RSAD1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RSAD1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RSAD1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RSAD1_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RSAD1_HUMAN

Related Literatures of Post-Translational Modification