RS7_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RS7_RAT
• UniProt AC: P62083
• Protein Name: 40S ribosomal protein S7
• Gene Name: Rps7
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 194
• Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with NEK6 in the centrosome.
• Protein Description: Required for rRNA maturation..
• Protein Sequence: MFSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MFSSSAKI -------CCCCCCEE	7.11	-
10	Ubiquitination	SSSAKIVKPNGEKPD CCCCEEECCCCCCCC	35.92	-
74	Acetylation	PQLKSFQKIQVRLVR CCCCCHHHHHHHHHH	32.85	22635317
85	Acetylation	RLVRELEKKFSGKHV HHHHHHHHHCCCCEE	72.28	22902405
88	Phosphorylation	RELEKKFSGKHVVFI HHHHHHCCCCEEEEE	56.67	25575281
90	Acetylation	LEKKFSGKHVVFIAQ HHHHCCCCEEEEEEE	31.84	22902405
119	Phosphorylation	NKQKRPRSRTLTAVH CCCCCCCHHCHHHHH	32.09	27097102
121	Phosphorylation	QKRPRSRTLTAVHDA CCCCCHHCHHHHHHH	29.70	23984901
123	Phosphorylation	RPRSRTLTAVHDAIL CCCHHCHHHHHHHHH	26.48	23984901
155	Acetylation	LDGSRLIKVHLDKAQ ECCCEEEEEEHHHHH	28.35	22902405
169	Acetylation	QQNNVEHKVETFSGV HHCCCCHHHHEEHHH	28.41	22902405
172	Phosphorylation	NVEHKVETFSGVYKK CCCHHHHEEHHHHHH	26.53	23984901
174	Phosphorylation	EHKVETFSGVYKKLT CHHHHEEHHHHHHHH	34.47	23984901
178	Acetylation	ETFSGVYKKLTGKDV HEEHHHHHHHHCCCC	38.61	22902405
179	Acetylation	TFSGVYKKLTGKDVN EEHHHHHHHHCCCCC	33.33	22902405
183	Acetylation	VYKKLTGKDVNFEFP HHHHHHCCCCCCCCC	53.95	22902405

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RS7_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RS7_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RS7_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of RS7_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.