RS7_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RS7_MOUSE
• UniProt AC: P62082
• Protein Name: 40S ribosomal protein S7
• Gene Name: Rps7
• Organism: Mus musculus (Mouse).
• Sequence Length: 194
• Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with NEK6 in the centrosome.
• Protein Description: Required for rRNA maturation..
• Protein Sequence: MFSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MFSSSAKI -------CCCCCCEE	7.11	-
3	Phosphorylation	-----MFSSSAKIVK -----CCCCCCEEEC	23.29	-
4	Phosphorylation	----MFSSSAKIVKP ----CCCCCCEEECC	24.05	29514104
10	Ubiquitination	SSSAKIVKPNGEKPD CCCCEEECCCCCCCC	35.92	-
15	Acetylation	IVKPNGEKPDEFESG EECCCCCCCCHHHCC	60.20	2373179
15	Ubiquitination	IVKPNGEKPDEFESG EECCCCCCCCHHHCC	60.20	22790023
37	Ubiquitination	LEMNSDLKAQLRELN HHCCCCHHHHHHHCC	38.79	22790023
49	Ubiquitination	ELNITAAKEIEVGGG HCCCCEEEEEEECCC	57.68	22790023
74	Acetylation	PQLKSFQKIQVRLVR CCCCCHHHHHHHHHH	32.85	23864654
74	Ubiquitination	PQLKSFQKIQVRLVR CCCCCHHHHHHHHHH	32.85	-
74	Malonylation	PQLKSFQKIQVRLVR CCCCCHHHHHHHHHH	32.85	26320211
85	Ubiquitination	RLVRELEKKFSGKHV HHHHHHHHHCCCCEE	72.28	22790023
90	Malonylation	LEKKFSGKHVVFIAQ HHHHCCCCEEEEEEE	31.84	26320211
90	Acetylation	LEKKFSGKHVVFIAQ HHHHCCCCEEEEEEE	31.84	23806337
119	Phosphorylation	NKQKRPRSRTLTAVH CCCCCCCHHCHHHHH	32.09	26643407
121	Phosphorylation	QKRPRSRTLTAVHDA CCCCCHHCHHHHHHH	29.70	26239621
123	Phosphorylation	RPRSRTLTAVHDAIL CCCHHCHHHHHHHHH	26.48	26239621
142	Ubiquitination	FPSEIVGKRIRVKLD CCHHHCCCEEEEEEC	33.48	-
147	Malonylation	VGKRIRVKLDGSRLI CCCEEEEEECCCEEE	30.89	26320211
155	Acetylation	LDGSRLIKVHLDKAQ ECCCEEEEEEHHHHH	28.35	23201123
155	Ubiquitination	LDGSRLIKVHLDKAQ ECCCEEEEEEHHHHH	28.35	-
155	Malonylation	LDGSRLIKVHLDKAQ ECCCEEEEEEHHHHH	28.35	26320211
160	Succinylation	LIKVHLDKAQQNNVE EEEEEHHHHHHCCCC	55.22	23806337
160	Acetylation	LIKVHLDKAQQNNVE EEEEEHHHHHHCCCC	55.22	23806337
160	Ubiquitination	LIKVHLDKAQQNNVE EEEEEHHHHHHCCCC	55.22	-
169	Acetylation	QQNNVEHKVETFSGV HHCCCCHHHHEEHHH	28.41	23864654
174	Phosphorylation	EHKVETFSGVYKKLT CHHHHEEHHHHHHHH	34.47	29514104
177	Phosphorylation	VETFSGVYKKLTGKD HHEEHHHHHHHHCCC	13.11	29514104
178	Succinylation	ETFSGVYKKLTGKDV HEEHHHHHHHHCCCC	38.61	23806337
178	Acetylation	ETFSGVYKKLTGKDV HEEHHHHHHHHCCCC	38.61	23806337
178	Ubiquitination	ETFSGVYKKLTGKDV HEEHHHHHHHHCCCC	38.61	-
183	Acetylation	VYKKLTGKDVNFEFP HHHHHHCCCCCCCCC	53.95	23954790
183	Ubiquitination	VYKKLTGKDVNFEFP HHHHHHCCCCCCCCC	53.95	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RS7_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RS7_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RS7_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RS7_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.