RS5_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RS5_MOUSE
• UniProt AC: P97461
• Protein Name: 40S ribosomal protein S5
• Gene Name: Rps5
• Organism: Mus musculus (Mouse).
• Sequence Length: 204
• Protein Sequence: MTEWEAATPAVAETPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKNIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MTEWEAAT -------CCHHHCCC	7.46	-
2	Acetylation	------MTEWEAATP ------CCHHHCCCC	50.21	-
2	Phosphorylation	------MTEWEAATP ------CCHHHCCCC	50.21	25619855
8	Phosphorylation	MTEWEAATPAVAETP CCHHHCCCCCCCCCC	20.87	26824392
14	Phosphorylation	ATPAVAETPDIKLFG CCCCCCCCCCCEEEC	19.27	25619855
18	Acetylation	VAETPDIKLFGKWST CCCCCCCEEECCCCC	45.18	23954790
22	Acetylation	PDIKLFGKWSTDDVQ CCCEEECCCCCCCCE	30.54	23954790
22	Ubiquitination	PDIKLFGKWSTDDVQ CCCEEECCCCCCCCE	30.54	-
24	Phosphorylation	IKLFGKWSTDDVQIN CEEECCCCCCCCEEC	25.99	22817900
34	Phosphorylation	DVQINDISLQDYIAV CCEECCCCHHHHHHH	23.88	22817900
47	Acetylation	AVKEKYAKYLPHSAG HHHHHHHHHCCCHHH	44.20	23806337
47	Ubiquitination	AVKEKYAKYLPHSAG HHHHHHHHHCCCHHH	44.20	-
47	Succinylation	AVKEKYAKYLPHSAG HHHHHHHHHCCCHHH	44.20	23806337
52	Phosphorylation	YAKYLPHSAGRYAAK HHHHCCCHHHHHHHH	30.40	24899341
56	Phosphorylation	LPHSAGRYAAKRFRK CCCHHHHHHHHHHHH	15.25	26643407
66	Glutathionylation	KRFRKAQCPIVERLT HHHHHCCCCHHHHHH	2.72	24333276
66	S-nitrosylation	KRFRKAQCPIVERLT HHHHHCCCCHHHHHH	2.72	20925432
66	S-palmitoylation	KRFRKAQCPIVERLT HHHHHCCCCHHHHHH	2.72	28526873
66	S-nitrosocysteine	KRFRKAQCPIVERLT HHHHHCCCCHHHHHH	2.72	-
133	Phosphorylation	TRIGRAGTVRRQAVD CCCCCCCCHHCCCCC	15.17	22817900
142	Phosphorylation	RRQAVDVSPLRRVNQ HCCCCCCHHHHHHHH	17.47	28066266
155	Glutathionylation	NQAIWLLCTGAREAA HHHHHHHHHHHHHHH	2.86	24333276
155	S-nitrosylation	NQAIWLLCTGAREAA HHHHHHHHHHHHHHH	2.86	20925432
155	S-palmitoylation	NQAIWLLCTGAREAA HHHHHHHHHHHHHHH	2.86	28526873
155	S-nitrosocysteine	NQAIWLLCTGAREAA HHHHHHHHHHHHHHH	2.86	-
156	Phosphorylation	QAIWLLCTGAREAAF HHHHHHHHHHHHHHH	33.57	22006019
182	Acetylation	DELINAAKGSSNSYA HHHHHHHCCCCCCCC	57.84	22826441
191	Malonylation	SSNSYAIKKKDELER CCCCCCCCCHHHHHH	45.67	26320211
191	Succinylation	SSNSYAIKKKDELER CCCCCCCCCHHHHHH	45.67	23954790
191	Acetylation	SSNSYAIKKKDELER CCCCCCCCCHHHHHH	45.67	23864654
192	Acetylation	SNSYAIKKKDELERV CCCCCCCCHHHHHHH	60.38	2373275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
24	S	Phosphorylation	Kinase	CSNK2A1	P68400	GPS
34	S	Phosphorylation	Kinase	CSNK2A1	P68400	GPS

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RS5_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RS5_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RS5_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.