RS4X_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RS4X_MOUSE
• UniProt AC: P62702
• Protein Name: 40S ribosomal protein S4, X isoform
• Gene Name: Rps4x
• Organism: Mus musculus (Mouse).
• Sequence Length: 263
• Subcellular Localization: Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs..
• Protein Sequence: MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Acetylation	LKRVAAPKHWMLDKL HHHHHCCCCHHHHHC	45.21	23806337
22	Ubiquitination	PKHWMLDKLTGVFAP CCCHHHHHCCCCCCC	43.94	-
22	Acetylation	PKHWMLDKLTGVFAP CCCHHHHHCCCCCCC	43.94	22826441
37	Ubiquitination	RPSTGPHKLRECLPL CCCCCCCHHHHHHHH	52.99	-
41	S-palmitoylation	GPHKLRECLPLIIFL CCCHHHHHHHHHHHH	3.71	28526873
41	S-nitrosylation	GPHKLRECLPLIIFL CCCHHHHHHHHHHHH	3.71	22178444
41	S-nitrosocysteine	GPHKLRECLPLIIFL CCCHHHHHHHHHHHH	3.71	-
41	Glutathionylation	GPHKLRECLPLIIFL CCCHHHHHHHHHHHH	3.71	24333276
53	Acetylation	IFLRNRLKYALTGDE HHHHHCHHHHHHHHH	25.82	22826441
53	Ubiquitination	IFLRNRLKYALTGDE HHHHHCHHHHHHHHH	25.82	-
54	Phosphorylation	FLRNRLKYALTGDEV HHHHCHHHHHHHHHH	16.07	29514104
62	Acetylation	ALTGDEVKKICMQRF HHHHHHHHHHHHHHE	34.08	25057289
62	Ubiquitination	ALTGDEVKKICMQRF HHHHHHHHHHHHHHE	34.08	22790023
63	Ubiquitination	LTGDEVKKICMQRFI HHHHHHHHHHHHHEE	46.44	-
71	Ubiquitination	ICMQRFIKIDGKVRT HHHHHEEEECCEEEC	31.84	22790023
94	Acetylation	MDVISIDKTGENFRL EEEEEEECCCCCEEE	57.68	23954790
94	Ubiquitination	MDVISIDKTGENFRL EEEEEEECCCCCEEE	57.68	-
106	Ubiquitination	FRLIYDTKGRFAVHR EEEEEECCCCEEEEE	45.23	22790023
120	Malonylation	RITPEEAKYKLCKVR ECCHHHHHHHEEEEE	46.31	26320211
120	Ubiquitination	RITPEEAKYKLCKVR ECCHHHHHHHEEEEE	46.31	-
120	Acetylation	RITPEEAKYKLCKVR ECCHHHHHHHEEEEE	46.31	23864654
121	Phosphorylation	ITPEEAKYKLCKVRK CCHHHHHHHEEEEEE	19.08	-
128	Succinylation	YKLCKVRKIFVGTKG HHEEEEEEEEECCCC	43.41	23806337
128	Acetylation	YKLCKVRKIFVGTKG HHEEEEEEEEECCCC	43.41	23806337
133	Phosphorylation	VRKIFVGTKGIPHLV EEEEEECCCCCCCEE	22.31	22817900
134	Acetylation	RKIFVGTKGIPHLVT EEEEECCCCCCCEEC	49.25	23806337
134	Ubiquitination	RKIFVGTKGIPHLVT EEEEECCCCCCCEEC	49.25	-
134	Succinylation	RKIFVGTKGIPHLVT EEEEECCCCCCCEEC	49.25	23806337
141	Phosphorylation	KGIPHLVTHDARTIR CCCCCEECCCCCCCC	22.02	22817900
155	Ubiquitination	RYPDPLIKVNDTIQI CCCCCEEEECCEEEE	42.54	22790023
168	Ubiquitination	QIDLETGKITDFIKF EEECCCCCEEEEEEE	50.26	22790023
181	S-palmitoylation	KFDTGNLCMVTGGAN EECCCCEEEEECCCC	2.09	28526873
181	S-nitrosylation	KFDTGNLCMVTGGAN EECCCCEEEEECCCC	2.09	22178444
181	Glutathionylation	KFDTGNLCMVTGGAN EECCCCEEEEECCCC	2.09	24333276
204	Phosphorylation	NRERHPGSFDVVHVK CCCCCCCCEEEEEEE	23.79	26824392
211	Succinylation	SFDVVHVKDANGNSF CEEEEEEECCCCCCE	35.92	23954790
211	Acetylation	SFDVVHVKDANGNSF CEEEEEEECCCCCCE	35.92	23954790
211	Ubiquitination	SFDVVHVKDANGNSF CEEEEEEECCCCCCE	35.92	-
217	Phosphorylation	VKDANGNSFATRLSN EECCCCCCEEEEEEE	20.04	23984901
220	Phosphorylation	ANGNSFATRLSNIFV CCCCCEEEEEEEEEE	30.08	23984901
223	Phosphorylation	NSFATRLSNIFVIGK CCEEEEEEEEEEECC	25.29	27180971
233	Ubiquitination	FVIGKGNKPWISLPR EEECCCCCCEEECCC	50.85	-
233	Succinylation	FVIGKGNKPWISLPR EEECCCCCCEEECCC	50.85	-
233	Acetylation	FVIGKGNKPWISLPR EEECCCCCCEEECCC	50.85	23806337
233	Malonylation	FVIGKGNKPWISLPR EEECCCCCCEEECCC	50.85	26320211
261	Phosphorylation	KRLAAKQSSG----- HHHHHHHCCC-----	36.00	29514104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RS4X_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RS4X_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RS4X_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RS4X_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.