RS3A_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RS3A_RAT
• UniProt AC: P49242
• Protein Name: 40S ribosomal protein S3a {ECO:0000255|HAMAP-Rule:MF_03122}
• Gene Name: Rps3a
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 264
• Subcellular Localization: Cytoplasm . Nucleus . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
• Protein Description: May play a role during erythropoiesis through regulation of transcription factor DDIT3..
• Protein Sequence: MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGGSSGKTTGDETGAKVERADGYEPPVQESV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Acetylation	GKKGAKKKVVDPFSK CCCCCCCCCCCCCCC	46.94	22902405
27	Acetylation	KVVDPFSKKDWYDVK CCCCCCCCCCCCCCC	55.95	22902405
28	Succinylation	VVDPFSKKDWYDVKA CCCCCCCCCCCCCCC	52.90	26843850
34	Acetylation	KKDWYDVKAPAMFNI CCCCCCCCCCEEEEE	45.84	-
56	Acetylation	VTRTQGTKIASDGLK EEECCCCEECCCCCC	43.00	-
85	Acetylation	EVAFRKFKLITEDVQ HHHHHHCCEECCCCC	41.85	22902405
119	Phosphorylation	SMVKKWQTMIEAHVD HHHHHHHHHHHHCCC	20.99	23984901
143	Phosphorylation	RLFCVGFTKKRNNQI HHHHEEEECCCCCCC	29.72	23984901
153	Phosphorylation	RNNQIRKTSYAQHQQ CCCCCCCCHHHHHHH	19.68	23984901
154	Phosphorylation	NNQIRKTSYAQHQQV CCCCCCCHHHHHHHH	22.85	23984901
155	ADP-ribosylation	NQIRKTSYAQHQQVR CCCCCCHHHHHHHHH	18.60	-
155	Phosphorylation	NQIRKTSYAQHQQVR CCCCCCHHHHHHHHH	18.60	23984901
182	Acetylation	EVQTNDLKEVVNKLI HHCCCCHHHHHHHHC	51.86	22902405
192	Phosphorylation	VNKLIPDSIGKDIEK HHHHCCHHHCHHHHH	28.08	23984901
195	Acetylation	LIPDSIGKDIEKACQ HCCHHHCHHHHHHHH	54.59	22902405
222	Acetylation	VKMLKKPKFELGKLM HHCCCCCCCCHHHHE	61.42	72604587
237	Phosphorylation	ELHGEGGSSGKTTGD EECCCCCCCCCCCCC	46.93	29779826
238	Phosphorylation	LHGEGGSSGKTTGDE ECCCCCCCCCCCCCC	47.81	27097102
241	Phosphorylation	EGGSSGKTTGDETGA CCCCCCCCCCCCCCC	39.27	28432305
242	Phosphorylation	GGSSGKTTGDETGAK CCCCCCCCCCCCCCC	46.23	28432305
246	Phosphorylation	GKTTGDETGAKVERA CCCCCCCCCCCCEEC	47.37	28432305
249	Acetylation	TGDETGAKVERADGY CCCCCCCCCEECCCC	46.07	148941
256	Phosphorylation	KVERADGYEPPVQES CCEECCCCCCCCCCC	26.30	28689409
263	Phosphorylation	YEPPVQESV------ CCCCCCCCC------	18.94	23712012

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RS3A_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RS3A_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RS3A_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of RS3A_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.