RS3A_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RS3A_DROME
• UniProt AC: P55830
• Protein Name: 40S ribosomal protein S3a {ECO:0000255|HAMAP-Rule:MF_03122}
• Gene Name: RpS3A {ECO:0000255|HAMAP-Rule:MF_03122}
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 268
• Subcellular Localization: Cytoplasm .
• Protein Description: Essential for oogenesis; required for late follicle cell development..
• Protein Sequence: MAVGKNKGLSKGGKKGGKKKVVDPFSRKDWYDVKAPNMFQTRQIGKTLVNRTQGQRIASDYLKGRVFEVSLADLQKDIDPERSFRKFRLIAEDVQDRNVLCNFHGMDLTTDKYRSMVKKWQTLIEAIVEAKTVDGYLLRVFCIGFTAKDQQSQRKTCYAQQSQVRKIRARMTDIITNEVSGADLKQLVNKLALDSIAKDIEKSCQRIYPLHDVYIRKVKVLKKPRFDVSKLLELHGDGGGKSVEAVVSSEGAVIDRPEGYEPPVQEAV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
34	Ubiquitination	RKDWYDVKAPNMFQT CCCCCCCCCCCCCCC	56.05	31113955
41	Phosphorylation	KAPNMFQTRQIGKTL CCCCCCCCCCCCCHH	17.18	21082442
46	Acetylation	FQTRQIGKTLVNRTQ CCCCCCCCHHHHHCC	40.07	21791702
46	Acetylation	FQTRQIGKTLVNRTQ CCCCCCCCHHHHHCC	40.07	-
59	Phosphorylation	TQGQRIASDYLKGRV CCCHHHHHHHHCCCE	25.15	27626673
63	Acetylation	RIASDYLKGRVFEVS HHHHHHHCCCEEEEE	38.14	21791702
63	Acetylation	RIASDYLKGRVFEVS HHHHHHHCCCEEEEE	38.14	-
70	Phosphorylation	KGRVFEVSLADLQKD CCCEEEEEHHHHHCC	15.61	21082442
83	Phosphorylation	KDIDPERSFRKFRLI CCCCHHHCHHHEEEE	27.95	27626673
112	Acetylation	GMDLTTDKYRSMVKK CCCCCHHHHHHHHHH	40.23	21791702
112	Acetylation	GMDLTTDKYRSMVKK CCCCCHHHHHHHHHH	40.23	-
198	Acetylation	LALDSIAKDIEKSCQ HHHHHHHHHHHHHHH	58.53	21791702
198	Acetylation	LALDSIAKDIEKSCQ HHHHHHHHHHHHHHH	58.53	-
229	Phosphorylation	KKPRFDVSKLLELHG CCCCCCHHHHHHHCC	21.30	22817900
242	Phosphorylation	HGDGGGKSVEAVVSS CCCCCCCEEEEEEEC	28.59	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RS3A_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RS3A_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RS3A_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RPB11_DROME	Rpb11	physical	14605208
LST8_DROME	Lst8	physical	14605208
DCR1_DROME	Dcr-1	physical	14605208
ATRIP_DROME	mus304	physical	14605208

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.