RS2_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RS2_RAT
• UniProt AC: P27952
• Protein Name: 40S ribosomal protein S2
• Gene Name: Rps2
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 293
• Protein Sequence: MADDAGAAGGPGGPGGPGLGGRGGFRGGFGSGLRGRGRGRGRGRGRGRGARGGKAEDKEWIPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSVQRTQAPAVATT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MADDAGAAG ------CCCCCCCCC	24.32	-
58	Acetylation	RGGKAEDKEWIPVTK CCCCCCCCCCEEHHH	46.59	66707929
58	Ubiquitination	RGGKAEDKEWIPVTK CCCCCCCCCCEEHHH	46.59	-
58	Succinylation	RGGKAEDKEWIPVTK CCCCCCCCCCEEHHH	46.59	26843850
65	Acetylation	KEWIPVTKLGRLVKD CCCEEHHHHHHHHHC	49.53	72625781
65	Ubiquitination	KEWIPVTKLGRLVKD CCCEEHHHHHHHHHC	49.53	-
74	Acetylation	GRLVKDMKIKSLEEI HHHHHCCCCCCHHEE	58.05	72616033
77	Phosphorylation	VKDMKIKSLEEIYLF HHCCCCCCHHEEEEE	44.48	22673903
85	Phosphorylation	LEEIYLFSLPIKESE HHEEEEEECCCCHHH	30.55	23984901
133	Phosphorylation	AFVAIGDYNGHVGLG EEEEEECCCCCEEEC	20.17	-
176	Succinylation	YWGNKIGKPHTVPCK CCCCCCCCCCEECCE	36.78	26843850
179	Phosphorylation	NKIGKPHTVPCKVTG CCCCCCCEECCEEEC	34.37	23984901
223	Phosphorylation	MAGIDDCYTSARGCT HCCCCHHHHHHCCCC	15.66	-
230	Phosphorylation	YTSARGCTATLGNFA HHHHCCCCCCHHHHH	26.04	23984901
232	Phosphorylation	SARGCTATLGNFAKA HHCCCCCCHHHHHHH	19.62	23984901
245	Phosphorylation	KATFDAISKTYSYLT HHHHHHHHHHHHHCC	22.21	23984901
247	Phosphorylation	TFDAISKTYSYLTPD HHHHHHHHHHHCCHH	15.77	23984901
248	Phosphorylation	FDAISKTYSYLTPDL HHHHHHHHHHCCHHH	10.08	23984901
249	Phosphorylation	DAISKTYSYLTPDLW HHHHHHHHHCCHHHH	20.92	28432305
250	Phosphorylation	AISKTYSYLTPDLWK HHHHHHHHCCHHHHH	12.27	28432305
252	Phosphorylation	SKTYSYLTPDLWKET HHHHHHCCHHHHHHC	13.41	28432305
257	Acetylation	YLTPDLWKETVFTKS HCCHHHHHHCCCCCC	51.29	22902405
259	Phosphorylation	TPDLWKETVFTKSPY CHHHHHHCCCCCCHH	19.72	25575281
262	Phosphorylation	LWKETVFTKSPYQEF HHHHCCCCCCHHHHH	26.69	28432305
263	Acetylation	WKETVFTKSPYQEFT HHHCCCCCCHHHHHH	37.66	22902405
264	Phosphorylation	KETVFTKSPYQEFTD HHCCCCCCHHHHHHH	26.28	29779826
266	Phosphorylation	TVFTKSPYQEFTDHL CCCCCCHHHHHHHHH	27.97	23984901
270	Phosphorylation	KSPYQEFTDHLVKTH CCHHHHHHHHHHHHC	23.04	28432305
275	Acetylation	EFTDHLVKTHTRVSV HHHHHHHHHCCCCEE	40.73	22902405
275	Ubiquitination	EFTDHLVKTHTRVSV HHHHHHHHHCCCCEE	40.73	-
276	Phosphorylation	FTDHLVKTHTRVSVQ HHHHHHHHCCCCEEE	22.47	22673903
278	Phosphorylation	DHLVKTHTRVSVQRT HHHHHHCCCCEEECC	37.69	28432305
281	Phosphorylation	VKTHTRVSVQRTQAP HHHCCCCEEECCCCC	14.83	29779826
292	Phosphorylation	TQAPAVATT------ CCCCCCCCC------	26.83	30181290
293	Phosphorylation	QAPAVATT------- CCCCCCCC-------	27.20	29779826

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RS2_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RS2_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RS2_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of RS2_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.