RS25_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RS25_MOUSE
• UniProt AC: P62852
• Protein Name: 40S ribosomal protein S25
• Gene Name: Rps25
• Organism: Mus musculus (Mouse).
• Sequence Length: 125
• Protein Sequence: MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Acetylation	DAGKSAKKDKDPVNK HCCHHCCCCCCCCCC	70.49	23201123
20	Acetylation	GKSAKKDKDPVNKSG CHHCCCCCCCCCCCC	73.19	23201123
26	Phosphorylation	DKDPVNKSGGKAKKK CCCCCCCCCCHHCCC	47.80	-
29	Acetylation	PVNKSGGKAKKKKWS CCCCCCCHHCCCCCC	61.63	6569389
43	Acetylation	SKGKVRDKLNNLVLF CCCCHHHHHHCEEEE	42.42	23806337
43	Ubiquitination	SKGKVRDKLNNLVLF CCCCHHHHHHCEEEE	42.42	-
52	Malonylation	NNLVLFDKATYDKLC HCEEEEEHHHHHHHH	34.98	26320211
52	Succinylation	NNLVLFDKATYDKLC HCEEEEEHHHHHHHH	34.98	-
52	Succinylation	NNLVLFDKATYDKLC HCEEEEEHHHHHHHH	34.98	23806337
52	Ubiquitination	NNLVLFDKATYDKLC HCEEEEEHHHHHHHH	34.98	-
52	Acetylation	NNLVLFDKATYDKLC HCEEEEEHHHHHHHH	34.98	23806337
54	Phosphorylation	LVLFDKATYDKLCKE EEEEEHHHHHHHHHH	37.68	22499769
55	Phosphorylation	VLFDKATYDKLCKEV EEEEHHHHHHHHHHC	18.88	22499769
57	Ubiquitination	FDKATYDKLCKEVPN EEHHHHHHHHHHCCC	45.42	-
57	Malonylation	FDKATYDKLCKEVPN EEHHHHHHHHHHCCC	45.42	26320211
57	Acetylation	FDKATYDKLCKEVPN EEHHHHHHHHHHCCC	45.42	23806337
59	Glutathionylation	KATYDKLCKEVPNYK HHHHHHHHHHCCCCE	4.32	24333276
60	Malonylation	ATYDKLCKEVPNYKL HHHHHHHHHCCCCEE	72.66	26320211
60	Acetylation	ATYDKLCKEVPNYKL HHHHHHHHHCCCCEE	72.66	23864654
66	Malonylation	CKEVPNYKLITPAVV HHHCCCCEECCHHHH	39.80	26320211
66	Ubiquitination	CKEVPNYKLITPAVV HHHCCCCEECCHHHH	39.80	-
66	Acetylation	CKEVPNYKLITPAVV HHHCCCCEECCHHHH	39.80	23864654
69	Phosphorylation	VPNYKLITPAVVSER CCCCEECCHHHHCHH	18.68	20469934
74	Phosphorylation	LITPAVVSERLKIRG ECCHHHHCHHHHHCH	15.48	29176673
93	Phosphorylation	AALQELLSKGLIKLV HHHHHHHHCCHHHHH	36.98	30352176
94	Succinylation	ALQELLSKGLIKLVS HHHHHHHCCHHHHHH	58.67	-
94	Succinylation	ALQELLSKGLIKLVS HHHHHHHCCHHHHHH	58.67	23806337
94	Malonylation	ALQELLSKGLIKLVS HHHHHHHCCHHHHHH	58.67	26073543
94	Acetylation	ALQELLSKGLIKLVS HHHHHHHCCHHHHHH	58.67	23806337
94	Ubiquitination	ALQELLSKGLIKLVS HHHHHHHCCHHHHHH	58.67	-
98	Malonylation	LLSKGLIKLVSKHRA HHHCCHHHHHHHHCC	48.13	26320211
98	Acetylation	LLSKGLIKLVSKHRA HHHCCHHHHHHHHCC	48.13	23864654
98	Ubiquitination	LLSKGLIKLVSKHRA HHHCCHHHHHHHHCC	48.13	-
109	Phosphorylation	KHRAQVIYTRNTKGG HHCCEEEEECCCCCC	10.78	29514104
113	Phosphorylation	QVIYTRNTKGGDAPA EEEEECCCCCCCCCC	27.98	23140645
114	Malonylation	VIYTRNTKGGDAPAA EEEECCCCCCCCCCC	65.53	26073543
114	Ubiquitination	VIYTRNTKGGDAPAA EEEECCCCCCCCCCC	65.53	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RS25_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RS25_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RS25_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RS25_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.