RS24_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RS24_MOUSE
• UniProt AC: P62849
• Protein Name: 40S ribosomal protein S24
• Gene Name: Rps24
• Organism: Mus musculus (Mouse).
• Sequence Length: 133
• Protein Description: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits..
• Protein Sequence: MNDTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAGKKPKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MNDTVTIR -------CCCCEEEH	10.38	-
4	Phosphorylation	----MNDTVTIRTRK ----CCCCEEEHHHH	17.97	29514104
9	Phosphorylation	NDTVTIRTRKFMTNR CCCEEEHHHHHHHHH	34.07	-
14	Phosphorylation	IRTRKFMTNRLLQRK EHHHHHHHHHHHHHC	21.96	-
21	Ubiquitination	TNRLLQRKQMVIDVL HHHHHHHCCHHHEEE	29.77	-
37	Acetylation	PGKATVPKTEIREKL CCCCCCCHHHHHHHH	55.22	23864654
37	Ubiquitination	PGKATVPKTEIREKL CCCCCCCHHHHHHHH	55.22	-
49	Ubiquitination	EKLAKMYKTTPDVIF HHHHHHHCCCCCEEE	42.28	-
68	Ubiquitination	RTHFGGGKTTGFGMI ECCCCCCCCCCEEEH	46.30	-
68	Acetylation	RTHFGGGKTTGFGMI ECCCCCCCCCCEEEH	46.30	23236377
76	Phosphorylation	TTGFGMIYDSLDYAK CCCEEEHHHCHHHHH	7.21	25367039
78	Phosphorylation	GFGMIYDSLDYAKKN CEEEHHHCHHHHHHC	13.23	26643407
81	Phosphorylation	MIYDSLDYAKKNEPK EHHHCHHHHHHCCCC	26.13	22817900
83	Ubiquitination	YDSLDYAKKNEPKHR HHCHHHHHHCCCCHH	50.32	-
83	Succinylation	YDSLDYAKKNEPKHR HHCHHHHHHCCCCHH	50.32	23954790
83	Malonylation	YDSLDYAKKNEPKHR HHCHHHHHHCCCCHH	50.32	26320211
83	Acetylation	YDSLDYAKKNEPKHR HHCHHHHHHCCCCHH	50.32	23864654
84	Ubiquitination	DSLDYAKKNEPKHRL HCHHHHHHCCCCHHH	59.37	-
88	Ubiquitination	YAKKNEPKHRLARHG HHHHCCCCHHHHHCC	34.87	-
122	Acetylation	KKVRGTAKANVGAGK HHHHHHHHCCCCCCC	40.09	23806337
122	Succinylation	KKVRGTAKANVGAGK HHHHHHHHCCCCCCC	40.09	23806337
129	Succinylation	KANVGAGKKPKE--- HCCCCCCCCCCC---	66.42	26388266
132	Succinylation	VGAGKKPKE------ CCCCCCCCC------	82.19	26388266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RS24_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RS24_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RS24_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RS24_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale identification and evolution indexing of tyrosinephosphorylation sites from murine brain.";
Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.;
J. Proteome Res. 7:311-318(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-81, AND MASSSPECTROMETRY.
PubMed: 18034455