dbPTM

RS21_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RS21_RAT
UniProt AC	P05765
Protein Name	40S ribosomal protein S21
Gene Name	Rps21
Organism	Rattus norvegicus (Rat).
Sequence Length	83
Subcellular Localization	Cytoplasm, cytosol . Cytoplasm . Rough endoplasmic reticulum . Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein Description
Protein Sequence	MQNDAGEFVDLYVPRKCSASNRIIAAKDHASIQMNVAEVDRSTGRFNGQFKTYGICGAIRRMGESDDSILRLAKADGIVSKNF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MQNDAGEF -------CCCCCCCE	8.29	3910104
27	Acetylation	SNRIIAAKDHASIQM CCCEEEECCCCEEEE	40.81	22902405
42	Phosphorylation	NVAEVDRSTGRFNGQ EEEEECCCCCCCCCE	30.65	25575281
43	Phosphorylation	VAEVDRSTGRFNGQF EEEECCCCCCCCCEE	33.02	25575281
51	Acetylation	GRFNGQFKTYGICGA CCCCCEEEECEEHHH	32.71	22902405
65	Phosphorylation	AIRRMGESDDSILRL HHHHCCCCCHHHHHH	40.77	27097102
68	Phosphorylation	RMGESDDSILRLAKA HCCCCCHHHHHHHHH	28.63	25575281
74	Acetylation	DSILRLAKADGIVSK HHHHHHHHHCCCCCC	52.15	22902405
81	Acetylation	KADGIVSKNF----- HHCCCCCCCC-----	52.02	22902405
81	Ubiquitination	KADGIVSKNF----- HHCCCCCCCC-----	52.02	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RS21_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RS21_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RS21_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RS21_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RS21_RAT

Related Literatures of Post-Translational Modification