dbPTM

RS18_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RS18_RAT
UniProt AC	P62271
Protein Name	40S ribosomal protein S18
Gene Name	Rps18
Organism	Rattus norvegicus (Rat).
Sequence Length	152
Subcellular Localization	Cytoplasm.
Protein Description	Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA..
Protein Sequence	MSLVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVGVSKKK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSLVIPEKF ------CCCCCHHHH	31.20	-
2	Phosphorylation	------MSLVIPEKF ------CCCCCHHHH	31.20	22673903
8	Acetylation	MSLVIPEKFQHILRV CCCCCHHHHHHHHHH	44.99	22902405
47	Succinylation	YAHVVLRKADIDLTK HHHHEEECCCCCCHH	46.37	26843850
60	Phosphorylation	TKRAGELTEDEVERV HHHCCCCCHHHHHHH	36.77	25575281
78	Acetylation	MQNPRQYKIPDWFLN CCCCCHHCCCHHHHC	39.15	22902405
91	Acetylation	LNRQKDVKDGKYSQV HCCCCCCCCCCHHHH	71.54	72614945
94	Acetylation	QKDVKDGKYSQVLAN CCCCCCCCHHHHHHC	52.44	22902405
95	Phosphorylation	KDVKDGKYSQVLANG CCCCCCCHHHHHHCC	15.18	23984901
96	Phosphorylation	DVKDGKYSQVLANGL CCCCCCHHHHHHCCC	19.80	23984901
106	Acetylation	LANGLDNKLREDLER HHCCCCHHHHHHHHH	48.89	22902405

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RS18_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RS18_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RS18_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RS18_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RS18_RAT

Related Literatures of Post-Translational Modification