RS18_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RS18_MOUSE
• UniProt AC: P62270
• Protein Name: 40S ribosomal protein S18
• Gene Name: Rps18
• Organism: Mus musculus (Mouse).
• Sequence Length: 152
• Subcellular Localization: Cytoplasm.
• Protein Description: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA..
• Protein Sequence: MSLVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVGVSKKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSLVIPEKF ------CCCCCHHHH	31.20	-
2	Phosphorylation	------MSLVIPEKF ------CCCCCHHHH	31.20	26824392
8	Acetylation	MSLVIPEKFQHILRV CCCCCHHHHHHHHHH	44.99	22826441
8	Ubiquitination	MSLVIPEKFQHILRV CCCCCHHHHHHHHHH	44.99	22790023
31	Phosphorylation	RKIAFAITAIKGVGR HHHHHHHHHHCCCCH	20.92	22006019
54	Acetylation	KADIDLTKRAGELTE CCCCCCHHHCCCCCH	47.77	7622479
54	Ubiquitination	KADIDLTKRAGELTE CCCCCCHHHCCCCCH	47.77	22790023
60	Phosphorylation	TKRAGELTEDEVERV HHHCCCCCHHHHHHH	36.77	30352176
78	Acetylation	MQNPRQYKIPDWFLN CCCCCHHCCCHHHHC	39.15	23954790
78	Ubiquitination	MQNPRQYKIPDWFLN CCCCCHHCCCHHHHC	39.15	22790023
91	Acetylation	LNRQKDVKDGKYSQV HCCCCCCCCCCHHHH	71.54	23864654
94	Acetylation	QKDVKDGKYSQVLAN CCCCCCCCHHHHHHC	52.44	23864654
94	Malonylation	QKDVKDGKYSQVLAN CCCCCCCCHHHHHHC	52.44	26320211
96	Phosphorylation	DVKDGKYSQVLANGL CCCCCCHHHHHHCCC	19.80	26370283
106	Acetylation	LANGLDNKLREDLER HHCCCCHHHHHHHHH	48.89	23236377
106	Ubiquitination	LANGLDNKLREDLER HHCCCCHHHHHHHHH	48.89	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RS18_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RS18_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RS18_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RS18_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.