| UniProt ID | RRP1_MOUSE | |
|---|---|---|
| UniProt AC | P56183 | |
| Protein Name | Ribosomal RNA processing protein 1 homolog A | |
| Gene Name | Rrp1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 494 | |
| Subcellular Localization | Nucleus, nucleolus. | |
| Protein Description | Plays a critical role in the generation of 28S rRNA.. | |
| Protein Sequence | MVPGVPLPPEIQLAQRLAGNEQVTRDRALRKLRKYIEARSQRATGGFTPDELLKVWKGLFYCMWMQDKPLQQEELGRTIAQLVHAFHTTEAQHQFLKAFWQTMIREWVGIDRLRLDKFYMLMRMVLSESLKAVKARGWDERQIEQLLELLTTEILNPDSQAPSGVKSHFLEIFLEELAKVGAAELTADQNLQFIDPFCQIAARTKDSQVLHKIIQSIFQTIVEQAPLAIEDIMNELDTQSGEGEASDGDDGEASDGDDGEASDDDDGEASDGGDGDVADSDDSDGADDDDGDVSDGDGGDNDEGDSNKSSEGEQDLQDTPPKKLPAGTAHRAGPEADKEQAWDDEENAGPVLQFDYEALANRLFKLASRQSTPSQNRKRLYKVIQKLRELAGGTFPEDDVPEKAYKKMLEGRRERKKKKKRLPKPQPQNKEAGSEAESSSADPGPGRKRKRNRKTDEKAGQGGPPGKRRKPGARAKGAGAQQPKKRIQSSQSAE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 24 | Phosphorylation | LAGNEQVTRDRALRK HCCCCCHHHHHHHHH | 26.92 | 26824392 | |
| 61 | Phosphorylation | KVWKGLFYCMWMQDK HHHHHHHHHHHHCCC | 6.09 | - | |
| 68 | Ubiquitination | YCMWMQDKPLQQEEL HHHHHCCCCCCHHHH | 30.64 | - | |
| 129 | Phosphorylation | MRMVLSESLKAVKAR HHHHHHHHHHHHHHC | 31.62 | 23140645 | |
| 254 | Phosphorylation | DGDDGEASDGDDGEA CCCCCCCCCCCCCCC | 37.51 | - | |
| 309 | Phosphorylation | DEGDSNKSSEGEQDL CCCCCCCCCCCCCCC | 37.56 | 25195567 | |
| 310 | Phosphorylation | EGDSNKSSEGEQDLQ CCCCCCCCCCCCCCC | 51.75 | 25619855 | |
| 319 | Phosphorylation | GEQDLQDTPPKKLPA CCCCCCCCCCCCCCC | 28.64 | 25619855 | |
| 365 | Ubiquitination | ALANRLFKLASRQST HHHHHHHHHHHCCCC | 47.97 | 22790023 | |
| 434 | Phosphorylation | PQNKEAGSEAESSSA CCCHHCCCHHHHCCC | 40.45 | 27087446 | |
| 438 | Phosphorylation | EAGSEAESSSADPGP HCCCHHHHCCCCCCC | 36.32 | 27087446 | |
| 439 | Phosphorylation | AGSEAESSSADPGPG CCCHHHHCCCCCCCC | 22.50 | 27087446 | |
| 440 | Phosphorylation | GSEAESSSADPGPGR CCHHHHCCCCCCCCC | 46.07 | 27087446 | |
| 455 | Phosphorylation | KRKRNRKTDEKAGQG CCCCCCCCCHHCCCC | 46.27 | - | |
| 489 | Phosphorylation | QPKKRIQSSQSAE-- CCHHHHHCCCCCC-- | 28.15 | 25266776 | |
| 490 | Phosphorylation | PKKRIQSSQSAE--- CHHHHHCCCCCC--- | 16.27 | 18846507 | |
| 492 | Phosphorylation | KRIQSSQSAE----- HHHHCCCCCC----- | 35.99 | 29550500 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RRP1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RRP1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RRP1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of RRP1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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