dbPTM

RRP15_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RRP15_DROME
UniProt AC	Q9VFE6
Protein Name	RRP15-like protein
Gene Name	CG3817
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	276
Subcellular Localization
Protein Description
Protein Sequence	MALLTEKRVKKTHAPASDSSPEESDSEGSQNSASEAEGNAGWADSIQKVLKTTKPKTQKKTVLARAKKSQAAVRFQKDAANKKPGFDFEIEKADVKEEDEGDNHEDEKPQASALDATLTKQQRKNVPLQLRVKPSFRDMERERTLRKVATRGVVQFFNAVRIQQKDLQQQLEEAGPLDSRQDAVLNNINKRKFLDVLMSGKRAKSTPVDNAVKKEEQETDDDDEDKGSSGKKKSEWSVLREDFMTNKKIKHWDEEDDDEEGHNDEADDSDYDDGEE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Acetylation	-MALLTEKRVKKTHA -CCCCCHHHCHHCCC	58.20	21791702
83	Acetylation	QKDAANKKPGFDFEI HHHHHHCCCCCCEEE	50.62	21791702
219	Phosphorylation	VKKEEQETDDDDEDK CHHHHHCCCCCCCCC	44.41	19429919
269	Phosphorylation	HNDEADDSDYDDGEE CCCCCCCCCCCCCCC	38.32	19429919
271	Phosphorylation	DEADDSDYDDGEE-- CCCCCCCCCCCCC--	21.64	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RRP15_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RRP15_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RRP15_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RRP15_DROME !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RRP15_DROME

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos."; Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.; J. Proteome Res. 7:1675-1682(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-269 AND TYR-271, ANDMASS SPECTROMETRY.	18327897 [Abstract]