RRNAD_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RRNAD_HUMAN
• UniProt AC: Q96FB5
• Protein Name: Protein RRNAD1
• Gene Name: RRNAD1
• Organism: Homo sapiens (Human).
• Sequence Length: 475
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MPGISARGLSHEGRKQLAVNLTRVLALYRSILDAYIIEFFTDNLWDTLPCSWQEALDGLKPPQLATMLLGMPGEGEVVRYRSVWPLTLLALKSTACALAFTRMPGFQTPSEFLENPSQSSRLTAPFRKHVRPKKQHEIRRLGELVKKLSDFTGCTQVVDVGSGQGHLSRFMALGLGLMVKSIEGDQRLVERAQRLDQELLQALEKEEKRNPQVVQTSPRHSPHHVVRWVDPTALCEELLLPLENPCQGRARLLLTGLHACGDLSVALLRHFSCCPEVVALASVGCCYMKLSDPGGYPLSQWVAGLPGYELPYRLREGACHALEEYAERLQKAGPGLRTHCYRAALETVIRRARPELRRPGVQGIPRVHELKIEEYVQRGLQRVGLDPQLPLNLAALQAHVAQENRVVAFFSLALLLAPLVETLILLDRLLYLQEQGFHAELLPIFSPELSPRNLVLVATKMPLGQALSVLETEDS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Acetylation	GLSHEGRKQLAVNLT CCCHHHHHHHHHHHH	61.59	25953088
15	Ubiquitination	GLSHEGRKQLAVNLT CCCHHHHHHHHHHHH	61.59	29967540
93	Phosphorylation	LTLLALKSTACALAF HHHHHHHHHHHHHHH	23.30	28111955
94	Phosphorylation	TLLALKSTACALAFT HHHHHHHHHHHHHHH	24.94	28111955
101	Phosphorylation	TACALAFTRMPGFQT HHHHHHHHCCCCCCC	22.05	28111955
108	Phosphorylation	TRMPGFQTPSEFLEN HCCCCCCCHHHHHHC	26.90	28111955
110	Phosphorylation	MPGFQTPSEFLENPS CCCCCCHHHHHHCCC	44.35	28111955
117	Phosphorylation	SEFLENPSQSSRLTA HHHHHCCCCCCCCCC	55.03	28111955
119	Phosphorylation	FLENPSQSSRLTAPF HHHCCCCCCCCCCCH	23.05	28111955
120	Phosphorylation	LENPSQSSRLTAPFR HHCCCCCCCCCCCHH	24.54	28111955
146	Ubiquitination	RRLGELVKKLSDFTG HHHHHHHHHHHHCCC	61.70	29967540
147	Ubiquitination	RLGELVKKLSDFTGC HHHHHHHHHHHCCCC	45.82	-
205	Ubiquitination	ELLQALEKEEKRNPQ HHHHHHHHHHHHCCC	72.52	29967540
216	Phosphorylation	RNPQVVQTSPRHSPH HCCCCCCCCCCCCCC	29.14	29214152
217	Phosphorylation	NPQVVQTSPRHSPHH CCCCCCCCCCCCCCC	11.66	29214152
221	Phosphorylation	VQTSPRHSPHHVVRW CCCCCCCCCCCEEEC	27.49	29214152
221 (in isoform 2)	Phosphorylation	-	27.49	25332170
296	Phosphorylation	KLSDPGGYPLSQWVA ECCCCCCCCHHHHCC	13.60	22210691
299	Phosphorylation	DPGGYPLSQWVAGLP CCCCCCHHHHCCCCC	19.93	22210691
331	Ubiquitination	EYAERLQKAGPGLRT HHHHHHHHHCCCHHH	60.96	-
347	Phosphorylation	CYRAALETVIRRARP HHHHHHHHHHHHHCH	23.29	23403867
371	Ubiquitination	IPRVHELKIEEYVQR CCCCCHHCHHHHHHH	45.12	33845483
459	Phosphorylation	RNLVLVATKMPLGQA CCEEEEEECCCHHHH	22.01	23532336

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RRNAD_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RRNAD_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RRNAD_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of RRNAD_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.