| UniProt ID | RRAS_MOUSE | |
|---|---|---|
| UniProt AC | P10833 | |
| Protein Name | Ras-related protein R-Ras | |
| Gene Name | Rras | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 218 | |
| Subcellular Localization |
Cell membrane Lipid-anchor Cytoplasmic side. Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS). |
|
| Protein Description | Regulates the organization of the actin cytoskeleton. With OSPBL3, modulates integrin beta-1 (ITGB1) activity.. | |
| Protein Sequence | MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPPSPPSAPRKKDGGCPCVLL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSSGAASGT ------CCCCCCCCC | 37.16 | 29514104 | |
| 3 | Phosphorylation | -----MSSGAASGTG -----CCCCCCCCCC | 31.02 | 29514104 | |
| 7 | Phosphorylation | -MSSGAASGTGRGRP -CCCCCCCCCCCCCC | 36.03 | 29514104 | |
| 9 | Phosphorylation | SSGAASGTGRGRPRG CCCCCCCCCCCCCCC | 22.62 | 29514104 | |
| 70 | S-nitrosocysteine | EDSYTKICTVDGIPA CCCCEEEEEECCCEE | 3.02 | - | |
| 70 | S-nitrosylation | EDSYTKICTVDGIPA CCCCEEEEEECCCEE | 3.02 | 21278135 | |
| 70 | S-palmitoylation | EDSYTKICTVDGIPA CCCCEEEEEECCCEE | 3.02 | 28526873 | |
| 97 | Phosphorylation | FGAMREQYMRAGNGF HHHHHHHHHHHCCCE | 5.47 | 29514104 | |
| 155 | Phosphorylation | NQRQVLRSEASSFSA HHHHHHHHHHHHCCC | 33.10 | - | |
| 192 | Ubiquitination | QLVRAVRKYQEQELP HHHHHHHHHHHHCCC | 44.69 | 22790023 | |
| 201 | Phosphorylation | QEQELPPSPPSAPRK HHHCCCCCCCCCCCC | 47.72 | 27180971 | |
| 204 | Phosphorylation | ELPPSPPSAPRKKDG CCCCCCCCCCCCCCC | 55.05 | 30635358 | |
| 215 | Methylation | KKDGGCPCVLL---- CCCCCCCCEEC---- | 3.81 | - | |
| 215 | Geranylgeranylation | KKDGGCPCVLL---- CCCCCCCCEEC---- | 3.81 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RRAS_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RRAS_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RRAS_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of RRAS_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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