dbPTM

RQL3_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RQL3_ARATH
UniProt AC	Q9FT72
Protein Name	ATP-dependent DNA helicase Q-like 3
Gene Name	RECQL3
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	713
Subcellular Localization	Nucleus.
Protein Description	3'-5' DNA helicase that may play a role in the repair of DNA. Exhibits an ATP or dATP-dependent DNA-helicase activity. Can not use GTP/dGTP, CTP/dCTP or UTP/dUTP as nucleotide cofactors. Catalyzes DNA strand annealing. On nicked Holliday junctions, unwinds the lagging strand. Cannot act on intact Holliday junctions..
Protein Sequence	MKKSPLPVQNVQSSDKNVAGKEALVKLLRWHFGHADFRGKQLEAIQAVVSGRDCFCLMPTGGGKSICYQIPALAKPGIVLVVSPLIALMENQVMALKEKGIAAEYLSSTQATHVKNKIHEDLDSGKPSVRLLYVTPELIATKGFMLKLRKLHSRGLLNLIAIDEAHCISSWGHDFRPSYRQLSTLRDSLADVPVLALTATAAPKVQKDVIDSLNLRNPLVLKSSFNRPNIFYEVRYKDLLDNAYTDLGNLLKSCGNICAIIYCLERTTCDDLSVHLSSIGISSAAYHAGLNSKMRSTVLDDWLSSKKQIIVATVAFGMGIDKKDVRMVCHFNIPKSMESFYQESGRAGRDQLPSRSVLYYGVDDRKKMEYLLRNSENKKSSSSKKPTSDFEQIVTYCEGSGCRRKKILESFGEEFPVQQCKKTCDACKHPNQVAHCLEELMTTASRRHNSSRIFITSSNNKTNEGQYSEFWNRNEDGSNSNEEISDSDDATEAANSVTGPKLSKKLGLDEKLVLLEQAEEKYYERNKQVKKSEKNAISEALRDSSKQRLLDALTRVLQLLACVEEIDSQKGSEFLENECYRKYSKAGKSFYYSQIASTVRWLGTASRDELMTRLSSVVSLAREQEPLEEPLLATEPVENIEEEDDGKTNTVESRVDEPTQELVVSPILSPIRLPQVPSFSEFVNRRKIKQNTLIDKSSEGFDDKKPAKIMKLQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
212	Phosphorylation	VQKDVIDSLNLRNPL HCHHHHHHCCCCCCE	14.18	19880383
305	Phosphorylation	VLDDWLSSKKQIIVA HHHHHHHCCCCEEEE	41.52	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RQL3_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RQL3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RQL3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RQL3_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RQL3_ARATH

Related Literatures of Post-Translational Modification