RPF1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RPF1_MOUSE
• UniProt AC: Q7TND5
• Protein Name: Ribosome production factor 1
• Gene Name: Rpf1
• Organism: Mus musculus (Mouse).
• Sequence Length: 349
• Subcellular Localization: Nucleus, nucleolus.
• Protein Description: May be required for ribosome biogenesis..
• Protein Sequence: MAKAGEKSVGGGKRGLKRKAAAEEPQEAAAASDGTAESGVQPAKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETTVDPNDEEVAYDEATDEFASYFNRQTSPKILITTSDRPHGRTVRLCEQLSTVIPDSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHVPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFKSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	Phosphorylation	PQEAAAASDGTAESG HHHHHHHCCCCHHCC	31.67	25619855
35	Phosphorylation	AAAASDGTAESGVQP HHHHCCCCHHCCCCC	32.04	25619855
38	Phosphorylation	ASDGTAESGVQPAKA HCCCCHHCCCCCCHH	41.63	25619855
182	Ubiquitination	RRGLALKKIIPQCIA HCCHHHHHHHHHHHH	46.87	22790023
193	Phosphorylation	QCIARDFTDLIVINE HHHHCCCCEEEEECC	33.90	-
331	Phosphorylation	FDSKYGEYEWVHKPR CCCCCCCEEEECCCC	15.66	29514104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RPF1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RPF1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RPF1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RPF1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.