RPC5_SCHPO - dbPTM
RPC5_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RPC5_SCHPO
UniProt AC O74883
Protein Name DNA-directed RNA polymerase III subunit rpc5
Gene Name rpc37
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 242
Subcellular Localization Cytoplasm . Nucleus .
Protein Description DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. The RPC53/RPC4-RPC37/RPC5 subcomplex is required for terminator recognition and reinitiation (By similarity)..
Protein Sequence MSFSEDQAMEEAKLRNDETEEQDPVVRTYPVFFSPGLRNNLLLNQFPLRPKNRTYSDANGEAPIDVRVKPKTGWMEVDVPIPTTKYYNEDKAMKYGNGKKPIQTQTLSGRLQKPRTNLMVGLIRDGQFHIVPLRGLTQLRPSMKHVNEYTQKLKAAAGPSNSSSGTSTPRGPIRAVQVTAKQNTEAPKVSTTHIVRATEEEEWVELDCRPERESESILKQLECPIEHQPNECAAVDEDYSFI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSFSEDQAM
------CCCCHHHHH
37.1624763107
4Phosphorylation----MSFSEDQAMEE
----CCCCHHHHHHH
32.7224763107
54PhosphorylationPLRPKNRTYSDANGE
CCCCCCCCCCCCCCC
36.4521712547
56PhosphorylationRPKNRTYSDANGEAP
CCCCCCCCCCCCCCC
29.6327738172
162PhosphorylationAAAGPSNSSSGTSTP
HHHCCCCCCCCCCCC
30.1625720772
163PhosphorylationAAGPSNSSSGTSTPR
HHCCCCCCCCCCCCC
36.7225720772
164PhosphorylationAGPSNSSSGTSTPRG
HCCCCCCCCCCCCCC
46.0029996109
166PhosphorylationPSNSSSGTSTPRGPI
CCCCCCCCCCCCCCE
31.2325720772
168PhosphorylationNSSSGTSTPRGPIRA
CCCCCCCCCCCCEEE
19.4929996109
216PhosphorylationRPERESESILKQLEC
CCHHHHHHHHHHCCC
42.3629996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RPC5_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RPC5_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RPC5_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of RPC5_SCHPO !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RPC5_SCHPO

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Related Literatures of Post-Translational Modification

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