RPAP2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RPAP2_ARATH
• UniProt AC: F4K1B1
• Protein Name: Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog
• Gene Name: At5g26760
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 735
• Subcellular Localization: Nucleus.
• Protein Description: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation..
• Protein Sequence: MAKDNEAIAINDAVHKLQLYMLENTTDQNQLFAARKLMSRSDYEDVVTERAIAKLCGYTLCQRFLPSDVSRRGKYRISLKDHKVYDLQETSKFCSAGCLIDSKTFSGSLQEARTLEFDSVKLNEILDLFGDSLEVKGSLDVNKDLDLSKLMIKENFGVRGEELSLEKWMGPSNAVEGYVPFDRSKSSNDSKATTQSNQEKHEMDFTSTVIMPDVNSVSKLPPQTKQASTVVESVDGKGKTVLKEQTVVPPTKKVSRFRREKEKEKKTFGVDGMGCAQEKTTVLPRKILSFCNEIEKDFKNFGFDEMGLASSAMMSDGYGVEYSVSKQPQCSMEDSLSCKLKGDLQTLDGKNTLSGSSSGSNTKGSKTKPEKSRKKIISVEYHANSYEDGEEILAAESYERHKAQDVCSSSEIVTKSCLKISGSKKLSRSVTWADQNDGRGDLCEVRNNDNAAGPSLSSNDIEDVNSLSRLALAEALATALSQAAEAVSSGNSDASDATAKAGIILLPSTHQLDEEVTEEHSEEEMTEEEPTLLKWPNKPGIPDSDLFDRDQSWFDGPPEGFNLTLSNFAVMWDSLFGWVSSSSLAYIYGKEESAHEEFLLVNGKEYPRRIIMVDGLSSEIKQTIAGCLARALPRVVTHLRLPIAISELEKGLGSLLETMSLTGAVPSFRVKEWLVIVLLFLDALSVSRIPRIAPYISNRDKILEGSGIGNEEYETMKDILLPLGRVPQFATRSGA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
148	Phosphorylation	VNKDLDLSKLMIKEN CCCCCCHHHHHHHHH	24.34	19880383
246	Phosphorylation	KTVLKEQTVVPPTKK CEEEEEEECCCCCHH	25.27	19880383
251	Phosphorylation	EQTVVPPTKKVSRFR EEECCCCCHHHHHHH	37.11	19880383
416	Phosphorylation	SSEIVTKSCLKISGS CCHHHHHHHHHCCCC	18.47	24894044
431	Phosphorylation	KKLSRSVTWADQNDG CCEEECEECCCCCCC	19.04	29654922
508	Phosphorylation	AGIILLPSTHQLDEE HCEEEECCCCCCCHH	38.19	23776212
509	Phosphorylation	GIILLPSTHQLDEEV CEEEECCCCCCCHHH	16.23	23776212
517	Phosphorylation	HQLDEEVTEEHSEEE CCCCHHHHHHCCHHH	38.65	23776212
521	Phosphorylation	EEVTEEHSEEEMTEE HHHHHHCCHHHCCCC	50.40	23776212
526	Phosphorylation	EHSEEEMTEEEPTLL HCCHHHCCCCCCCHH	43.45	23776212
531	Phosphorylation	EMTEEEPTLLKWPNK HCCCCCCCHHCCCCC	48.26	23776212
658	Phosphorylation	GLGSLLETMSLTGAV CHHHHHHHHHCCCCC	16.42	19880383
660	Phosphorylation	GSLLETMSLTGAVPS HHHHHHHHCCCCCCC	30.14	24243849

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RPAP2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RPAP2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RPAP2_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of RPAP2_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.