ROR2_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ROR2_DROME
• UniProt AC: Q9V6K3
• Protein Name: Tyrosine-protein kinase transmembrane receptor Ror2
• Gene Name: Nrk
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 724
• Subcellular Localization: Cell membrane; Single-pass type I membrane protein .
• Protein Description: Tyrosine-protein kinase receptor that functions during early stages of neuronal development..
• Protein Sequence: MAAGQWVGVVERVLRGMVLKWGANLAVLGLCVFLFASATHANSLNAIEEPVTRRHHQRHHEREREENGYCAPYSGKVCKEYLTGQVWYSLEDPTGGWKNEQVTTALWDELISDLTGLCREAAEKMLCAYAFPNCHMEGGRAVKAPLCFEDCQATHLQFCYNDWVLIEEKKERNMFIKSRGHFRLPNCSSLPHYNASMRRPNCSYIGLTELKESEVSYDCRNGNGRFYMGTMNVSKSGIPCQRWDTQYPHKHFQPPLVFHQLLEGENYCRNAGGEEPHPWCYTVDESVRWQHCDIPMCPDYVDPNAVDLNTPIKMEKFFTPSMIFLLAGIGFVAIVTLHLMILLVYKLSKHKDYSQPAGAATAECSVSMRGGGDCGGNLNTSRETLGGNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVYVRSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKGDENDFIPIRWMPLESILYNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDNTPLSVYALMRRCWNRKPSERPGFAEINHCIQHSIAESECKAML

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
186	N-linked_Glycosylation	RGHFRLPNCSSLPHY CCCCCCCCCCCCCCC	42.78	-
194	N-linked_Glycosylation	CSSLPHYNASMRRPN CCCCCCCCCCCCCCC	23.62	-
201	N-linked_Glycosylation	NASMRRPNCSYIGLT CCCCCCCCCCEEECE	26.09	-
232	N-linked_Glycosylation	RFYMGTMNVSKSGIP CEEEEEEEECCCCCC	34.45	-
606	Phosphorylation	FGLSHKIYLQDYYKG HCCCCEEEECCCCCC	11.78	-
610	Phosphorylation	HKIYLQDYYKGDEND CEEEECCCCCCCCCC	8.30	-
611	Phosphorylation	KIYLQDYYKGDENDF EEEECCCCCCCCCCC	19.45	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ROR2_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ROR2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ROR2_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of ROR2_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.