dbPTM

ROGFA_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ROGFA_ARATH
UniProt AC	Q1KS66
Protein Name	Rop guanine nucleotide exchange factor 10
Gene Name	ROPGEF10
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	493
Subcellular Localization
Protein Description	Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP..
Protein Sequence	MFDGRNSGHSSFSSRGDGMHTPEHELAGHAAPSTRRGKQNRRSDMEVMKERFAKLLLGEDMSGGGTGETSALALSNAITKLADSMFGEQMKLQPMYPETKENWRKEMGWLLSVIDHIVQFVPSRQMGKNGQFTEIMVTKQRDDLLTNIPALRKLDSVLLETLDNFKDQKDFWYVPRDMEDADHNGDWRRDENWWLPVVKVPTDGLSEESRRWLQNQKDSVAQVLKAATAINAHVLSEMHVPENYIDSLPKNGKTSLGDFLYKSITEESFDPDYFVSFLDLSTEHKVLDLKNRIEASMVIWKRKMCQKEKDGKSQWGSTVSLEKRELFEVRAETILVMLKQQFPGIPQSSLEVSKIKNNKDVGQAILESYSRVLESLASKIMSRIEDVLEADRLVQRQLMGEAETRSESEAESEYEETEKVVAAETPNSRKLSDFIGWRLSSDTKKHSSMSDIEFFHKVEQEKEKPMMKSPRALPKKFSYLAKLENMRSPSDRH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
202	Phosphorylation	LPVVKVPTDGLSEES EEEEECCCCCCCHHH		19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ROGFA_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ROGFA_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ROGFA_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ROGFA_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ROGFA_ARATH

Related Literatures of Post-Translational Modification