dbPTM

RN_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RN_DROME
UniProt AC	Q9VI93
Protein Name	Zinc finger protein rotund
Gene Name	rn {ECO:0000312\|FlyBase:FBgn0267337}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	946
Subcellular Localization	Nucleus .
Protein Description	Transcription factor involved in imaginal disks development. Isoform rn is required in the wings, antenna, haltere, proboscis and legs disks, while isoform roe is required in the eye disk. Together with nab corepressor, it is involved in the initiation and maintenance of wingless (wg) expression in the wing hinge, by limiting the expression of wg to this compartment. Also required for the epithelial-mesenchymal transition branch of basolateral junctions signaling..
Protein Sequence	MIMHGTWYKGPQLAHHPHSNPHNSSHGHSDYHQFRSYPSFVVTPYHDGHVQGPATPTPCTAPPTPCNGPVPVSVPVSIPVCHTGGQGSPVIVESSFAIAAAAAAAAAAVAVGGSSATPLLPSPPIKIEQVFGEPSSLGAVVEDYALGLDCPVEHTFRKPHNNNGYSWSTGNNNEVVSHSSNGHTNNHPTTPPTPPNEASATQATSVSAINLNQAQPASQTRSNFGSSIKSPPSEPDAVTAATCKSQENNSGQNPTPNSLSDHNPAHNLNSNSTAAAVAAAAAAAAAANMPIGGVQGQNPTQGLVHWMSAVMAEHMTGQTHHDPGAVGMHYMWNGNVDHAKDISDYNLWPPTPRSHQHASEHHPMSLKQEYEAKMNDHHHNNLQKGHFLDDNRLEHHAVTGQGGLGLGASNGVGGGGGGASVVGNSSLGASSHHAVAAAHHHNQAVAAASAAALLVVPQPINASKMGGPGGVSSVAGGHATGGGSGRKYQCKMCPQIFSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHAERTDKRPPIVPGSAAAIAAAAAAAAGGSANPANGPPPPPNPAQHQRNNLGLPPVSIAPSDNGYWPKVSPDSAAAANAMEVMHQQQQQQQQQQQQQQQQQQQQQQQAHHHHPQHGVPPQQHVPPQQQQQQQQQQQHHHPQQQPPPQHSMEAHYAQPTAPNGSQSNGHGAELQPHHRMPDPVREDIASTPSAVGPYDAASITKTTSNSAFTPINSMPPHLNSLSHHPMAQRPYLYDAISFPNKNVNQNNANAFPNQLISLHQIRNYAHQPAGLMAGEHLLGVSVGPGKDKG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of RN_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RN_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RN_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RN_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RN_DROME !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RN_DROME

Related Literatures of Post-Translational Modification