dbPTM

RNZ_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RNZ_DROME
UniProt AC	Q8MKW7
Protein Name	Ribonuclease Z, mitochondrial {ECO:0000303\|PubMed:14715923}
Gene Name	RNaseZ {ECO:0000303\|PubMed:14715923, ECO:0000312\|FlyBase:FBgn0028426}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	766
Subcellular Localization	Nucleus . Mitochondrion .
Protein Description	Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity of nuclear and mitochondrial pre-tRNA. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. May participate in tRNA processing in the developing embryo..
Protein Sequence	MYLVKSAGSPIYRTLRTLTTSNLMAATIASAKDPLTGPRYEREPNVLRKKLASVVPGTVNLQVLGSGANGAPAAVYLFTDQARYLFNCGEGTQRLAHEHKTRLSRLEQIFLTQNTWASCGGLPGLTLTIQDAGVRDIGLHGPPHLGSMLQSMRRFVVLKNLQVRPNDCSEGACFEDSILKVDSLPLINSEDPTKSVINYICQLKPRAGALNLVKCVEQGVPPGPLLGQLKNGNDITLPDGKVVRSVDVTEASETALSFVFLDVPSENYLPALLTHGKRLKKLGEEKLTEVALVVHFTPYHISSRQVYKDFVVESFSSEAQHIYLSSPLNQFSGYAAAHRIQHQLHQLAPQVFPLLGEQLSCQSQTLSLNLKKTKLDEADSEDKANAKANETEEQGVVAMTNYHLRPRKGLDRTLESKLTPEEYVKETHAVPGFLELLAKFKEEYSFPDNSADSYPKIIFLGTGSCIPNKTRNVSSILIRTAIDAYVLLDCGEGTYGQIVRLYGHEKGQLILRQLQAIYVSHLHADHHIGLIGLLRERRQLKPRADPLILLAPRQIEPWLEFYNRQIETVEDAYTLVGNGELLASPLSGEQVERLGITSISTCLVRHCPNSFGISLTLAAKHNSEPVKITYSGDTMPCQDLIDLGRDSTVLIHEATMEDDLEEEARLKTHSTVSQAIQQGRNMNARHTILTHFSQRYAKCPRLPSDEDMQRVAIAFDNMEVTIEDLQHYHKLYPALFAMYAEYTEELEQRAVKRELKQERKRKLAET

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of RNZ_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RNZ_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RNZ_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RNZ_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RNZ_DROME

Related Literatures of Post-Translational Modification