RNK_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RNK_HUMAN
• UniProt AC: Q6P5S7
• Protein Name: Ribonuclease kappa
• Gene Name: RNASEK
• Organism: Homo sapiens (Human).
• Sequence Length: 137
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds. Hydrolyzes UpU bonds at a lower rate..
• Protein Sequence: MGWLRPGPRPLCPPARASWAFSHRFPSPLAPRRSPTPFFMASLLCCGPKLAACGIVLSAWGVIMLIMLGIFFNVHSAVLIEDVPFTEKDFENGPQNIYNLYEQVSYNCFIAAGLYLLLGGFSFCQVRLNKRKEYMVR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
103	Ubiquitination	NIYNLYEQVSYNCFI CHHHHHHHHHHHHHH		21890473
124	S-palmitoylation	LLGGFSFCQVRLNKR HHCCCEEEEHHCCCC		29575903
132	Ubiquitination	QVRLNKRKEYMVR-- EHHCCCCHHHCCC--		21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RNK_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RNK_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RNK_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of RNK_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.