RNF14_MOUSE - dbPTM
RNF14_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RNF14_MOUSE
UniProt AC Q9JI90
Protein Name E3 ubiquitin-protein ligase RNF14
Gene Name Rnf14
Organism Mus musculus (Mouse).
Sequence Length 485
Subcellular Localization Cytoplasm. Nucleus.
Protein Description Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription (By similarity)..
Protein Sequence MSAEDLEAQEDELLALASIYDADEFRKAESVQGGETRIYLDLPQNFKIFVSGNSNESLQNSGFEYTICFLPPLVLNFELPPDYPSSSPPSFTLSGKWLSPTQLSALCKHLDNLWEEHRGRVVLFAWMQFLKEETLTYLNIVSPFELKMGSQKKVQRRATAQASSSTELGVGGAAAADVDQEETVDERAVQDVESLSSLIQEILDFNQARQTKCFNSKLFLCSICFCEKLGSDCMYFLECKHVYCKACLKDYFEIQIKDGQVKCLNCPEPQCPSVATPGQVKELVEADLFARYDRLLLQSTLDLMADVVYCPRPCCQLPVMQEPGGTMAICSSCNFAFCTLCRLTYHGLSPCKVTAEKLIDLRNEYLQADEATKRFLEQRYGKRVIQKALEEMESKDWLEKNSKSCPCCGTPIQKLDGCNKMTCTGCMQYFCWICMGSLSRANPYRHFTDSESPCFNRLFHAVDINGDMWEDEIEEDDDDEDDDDD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
257UbiquitinationDYFEIQIKDGQVKCL
HHEEEEEECCCEEEC
39.1622790023
349PhosphorylationRLTYHGLSPCKVTAE
HHHHCCCCCCCCCHH
32.6126824392
352UbiquitinationYHGLSPCKVTAEKLI
HCCCCCCCCCHHHHH
46.1022790023
357UbiquitinationPCKVTAEKLIDLRNE
CCCCCHHHHHHHHHH
48.5622790023
400SuccinylationESKDWLEKNSKSCPC
HCHHHHHHHCCCCCC
65.4323954790
400UbiquitinationESKDWLEKNSKSCPC
HCHHHHHHHCCCCCC
65.43-
450PhosphorylationPYRHFTDSESPCFNR
CCCCCCCCCCCHHHH
36.6020415495
452PhosphorylationRHFTDSESPCFNRLF
CCCCCCCCCHHHHHC
30.8122817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RNF14_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RNF14_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RNF14_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RNF14_MOUSE

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Related Literatures of Post-Translational Modification

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