dbPTM

RND2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RND2_MOUSE
UniProt AC	Q9QYM5
Protein Name	Rho-related GTP-binding protein RhoN
Gene Name	Rnd2
Organism	Mus musculus (Mouse).
Sequence Length	227
Subcellular Localization	Cytoplasmic vesicle, secretory vesicle, acrosome membrane Lipid-anchor Cytoplasmic side . Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome..
Protein Description	May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily..
Protein Sequence	MEGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRGHRQLRRTDSRRGLQRSTQLSGRPDRGNEGEMHKDRAKSCNLM

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
96	Phosphorylation	SRPETLDSVLKKWQG CCCHHHHHHHHHHCC	32.25	26745281
151	Ubiquitination	EQGTVLAKQVGAVSY CCCCEEEEEECCEEE	41.16	-
205	Phosphorylation	LQRSTQLSGRPDRGN HHHHHHCCCCCCCCC	23.96	24719451
223	Phosphorylation	MHKDRAKSCNLM--- CCHHHHHHCCCC---	13.78	-
224	Methylation	HKDRAKSCNLM---- CHHHHHHCCCC----	4.46	-
224	Geranylgeranylation	HKDRAKSCNLM---- CHHHHHHCCCC----	4.46	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RND2_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RND2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RND2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RND2_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RND2_MOUSE

Related Literatures of Post-Translational Modification