RN181_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RN181_MOUSE
• UniProt AC: Q9CY62
• Protein Name: E3 ubiquitin-protein ligase RNF181
• Gene Name: Rnf181
• Organism: Mus musculus (Mouse).
• Sequence Length: 165
• Protein Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates..
• Protein Sequence: MASYFDEHDCEPLNPEREARNNMLLELARRVRGAWSWAPGGRSLFNRMDFEDLGLVDWEHHLPPPAAKAVVESLPRTVISSAKADLKCPVCLLEFEAEETVIEMPCHHLFHSNCILPWLSKTNSCPLCRHELPTDDDSYEEHKKDKARRQQQQHRLENLHGAMYT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MASYFDEHDC -----CCCCCCHHCC	25.65	30635358
4	Phosphorylation	----MASYFDEHDCE ----CCCCCCHHCCC	12.91	30635358
83	Ubiquitination	RTVISSAKADLKCPV HHHHHHCCCCCCCCE	44.36	-
165	Phosphorylation	NLHGAMYT------- HHHHHCCC-------	21.03	28066266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RN181_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RN181_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RN181_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RN181_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.