RMXL3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RMXL3_HUMAN
• UniProt AC: Q8N7X1
• Protein Name: RNA-binding motif protein, X-linked-like-3
• Gene Name: RBMXL3
• Organism: Homo sapiens (Human).
• Sequence Length: 1067
• Protein Sequence: MMEADRPEKLFIGGLNLKTDEKALKAEFGKYGHIIKVFLMKDRKTNKSRGFAFVTFESPADAKAAARDMNGKYLDGKAIMVAQTIKPAFKSSRWVPPTPGSGSRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWASPPHKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVPRSSLARIGGSGMPGKAPAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDYRPLRGDGNQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGGGCRYEEYQGNSPDACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEEYQGRSLDANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDANSGGRSPDTHSGGHSSSSNSYGQSHRYGGEGRYEYRGRSHDAHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNAYSGGHNSSSRNDPCRGGGRYEENRGHSLDANSGGHSPNAYSGGRDSSSNSYDRSHRYGGGGHYEEYRGRSHDTHSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSDHYGRGGCYEEYQGRSPNAYGGGRGLNSSNNSHGRSHRYGGGGRYEEYRGPSPDAHSGGRDSSIKSYGLSDRYGGGGHYEEYQGSLPDAYSGDHDRSSNSYGRSDRYSRGRDRVGRPDRGLPLPMETGSPPLHDSYSRSGCRVPRGGGRQGGRFERGEGRSRY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
48	Phosphorylation	KDRKTNKSRGFAFVT CCCCCCCCCCEEEEE	39.44	23882029
49	Methylation	DRKTNKSRGFAFVTF CCCCCCCCCEEEEEE	45.95	-
55	Phosphorylation	SRGFAFVTFESPADA CCCEEEEEECCHHHH	18.41	30266825
58	Phosphorylation	FAFVTFESPADAKAA EEEEEECCHHHHHHH	22.61	29255136
63	Ubiquitination	FESPADAKAAARDMN ECCHHHHHHHHHHCC	38.82	16196087
117	Phosphorylation	RTRGGGSSPQRPPSQ CCCCCCCCCCCCCCC	28.46	22496350
150	Methylation	RAPMPRKRGPPPRHW CCCCCCCCCCCCCCC	65.22	-
173	Phosphorylation	TPSSLAHSVGCGMRG CHHHHHHHCCCCCCC	18.01	24425749
186	Phosphorylation	RGKAPTVSGQDGYSG CCCCCCCCCCCCCCC	32.96	28258704
191	Phosphorylation	TVSGQDGYSGLQPRR CCCCCCCCCCCCCCC	14.09	28258704
192	Phosphorylation	VSGQDGYSGLQPRRW CCCCCCCCCCCCCCC	38.26	28258704
211	Phosphorylation	HKRAVPRSSLARIGG CCCCCCHHHHHHCCC	24.51	27251275
212	Phosphorylation	KRAVPRSSLARIGGS CCCCCHHHHHHCCCC	27.59	27251275
219	Phosphorylation	SLARIGGSGMPGKAP HHHHCCCCCCCCCCC	27.06	27251275
263	Phosphorylation	LRDYSRRYYGHSSVP HHHHHHHHCCCCCCC	16.82	30206219
264	Phosphorylation	RDYSRRYYGHSSVPD HHHHHHHCCCCCCCC	13.42	30206219
267	Phosphorylation	SRRYYGHSSVPDYRP HHHHCCCCCCCCCCC	28.77	30206219
268	Phosphorylation	RRYYGHSSVPDYRPL HHHCCCCCCCCCCCC	31.81	30206219
272	Phosphorylation	GHSSVPDYRPLRGDG CCCCCCCCCCCCCCC	14.20	30206219
371	Phosphorylation	KAYSGGRSSSSNGYS CCCCCCCCCCCCCCC	37.54	24732914
372	Phosphorylation	AYSGGRSSSSNGYSR CCCCCCCCCCCCCCC	36.10	24732914
373	Phosphorylation	YSGGRSSSSNGYSRS CCCCCCCCCCCCCCC	29.12	24732914
374	Phosphorylation	SGGRSSSSNGYSRSD CCCCCCCCCCCCCCC	35.90	24732914
377	Phosphorylation	RSSSSNGYSRSDRYG CCCCCCCCCCCCCCC	12.74	29759185
410	Phosphorylation	GRNSSSNSYGQSHHY CCCCCCCCCCCCCCC	32.37	-
430	Phosphorylation	YEEYRGRSHEARSGG CHHHCCCCCCHHCCC	28.62	24719451
439	Phosphorylation	EARSGGRSTDAHSRG CHHCCCCCCCCHHCC	33.63	-
440	Phosphorylation	ARSGGRSTDAHSRGR HHCCCCCCCCHHCCC	35.53	-
459	Phosphorylation	YSGGHDSSSWSDCCG CCCCCCCCCHHHCCC	41.71	-
460	Phosphorylation	SGGHDSSSWSDCCGG CCCCCCCCHHHCCCC	34.25	-
492	Phosphorylation	GCSPEAYSGGHDNSS CCCHHHHCCCCCCCC	45.40	27251789
501	Phosphorylation	GHDNSSWSDRYGVGG CCCCCCHHHCCCCCC	17.73	27251789
517	Phosphorylation	YEENRGHSLDANSGG CCCCCCCCCCCCCCC	30.67	22210691
522	Phosphorylation	GHSLDANSGGRSPDT CCCCCCCCCCCCCCC	44.33	22210691
547	Phosphorylation	SYGQSHRYGGEGRYE CCCCCCCCCCCCCCE	24.86	29457462
559	Phosphorylation	RYEYRGRSHDAHSGG CCEECCCCCCCCCCC	28.66	-
564	Phosphorylation	GRSHDAHSGGCSADA CCCCCCCCCCCCCCC	38.30	-
568	Phosphorylation	DAHSGGCSADAYSGG CCCCCCCCCCCCCCC	32.24	-
580	Phosphorylation	SGGHDSSSQSNRYGG CCCCCCCCCCCCCCC	41.39	-
598	Phosphorylation	YEEYRGRSLDANSGG HHHHCCCCCCCCCCC	33.16	27174698
603	Phosphorylation	GRSLDANSGGRSPNA CCCCCCCCCCCCCCC	44.33	27174698
607	Phosphorylation	DANSGGRSPNAYSGG CCCCCCCCCCCCCCC	26.27	27174698
611	Phosphorylation	GGRSPNAYSGGHDSS CCCCCCCCCCCCCCC	17.94	27174698
612	Phosphorylation	GRSPNAYSGGHDSSS CCCCCCCCCCCCCCC	35.57	27174698
617	Phosphorylation	AYSGGHDSSSWSHRY CCCCCCCCCCCCCCC	22.16	27174698
618	Phosphorylation	YSGGHDSSSWSHRYG CCCCCCCCCCCCCCC	41.71	27174698
619	Phosphorylation	SGGHDSSSWSHRYGG CCCCCCCCCCCCCCC	36.23	27174698
621	Phosphorylation	GHDSSSWSHRYGGGG CCCCCCCCCCCCCCC	10.47	27174698
624	Phosphorylation	SSSWSHRYGGGGRYE CCCCCCCCCCCCCCC	18.07	27174698
646	Phosphorylation	DANSGGRSPDAYSGG CCCCCCCCCCCCCCC	30.33	22210691
650	Phosphorylation	GGRSPDAYSGGHDSS CCCCCCCCCCCCCCC	18.41	23663014
657	Phosphorylation	YSGGHDSSGQSNCYG CCCCCCCCCCCCCCC	47.08	22210691
660	Phosphorylation	GHDSSGQSNCYGGGG CCCCCCCCCCCCCCC	32.18	22210691
685	Phosphorylation	DANSGGRSPDAYSGG CCCCCCCCCCCCCCC	30.33	23663014
689	Phosphorylation	GGRSPDAYSGGHDSS CCCCCCCCCCCCCCC	18.41	23663014
690	Phosphorylation	GRSPDAYSGGHDSSS CCCCCCCCCCCCCCC	39.76	23663014
695	Phosphorylation	AYSGGHDSSSQSNRY CCCCCCCCCCCCCCC	26.64	23663014
696	Phosphorylation	YSGGHDSSSQSNRYG CCCCCCCCCCCCCCC	38.15	23663014
697	Phosphorylation	SGGHDSSSQSNRYGG CCCCCCCCCCCCCCC	41.39	23663014
699	Phosphorylation	GHDSSSQSNRYGGGG CCCCCCCCCCCCCCC	25.81	23663014
715	Phosphorylation	YEEYRGHSLDANSGG CCCCCCCCCCCCCCC	30.67	22210691
720	Phosphorylation	GHSLDANSGGRSPDT CCCCCCCCCCCCCCC	44.33	22210691
760	Phosphorylation	SGRLPDAYSGGHDSS CCCCCCCCCCCCCCC	18.41	22210691
761	Phosphorylation	GRLPDAYSGGHDSSS CCCCCCCCCCCCCCC	39.76	22210691
822	Methylation	GGRYEENRGHSLDAN CCCCCCCCCCCCCCC	47.70	115387697
852	Phosphorylation	SSNSYDRSHRYGGGG CCCCCCCCCCCCCCC	14.93	22210691
864	Phosphorylation	GGGHYEEYRGRSHDT CCCCCHHHCCCCCCC	13.36	22210691
871	Phosphorylation	YRGRSHDTHSRGRSP HCCCCCCCCCCCCCC	19.14	22210691
890	Phosphorylation	GDHYTEAYSRGRDSF CCCHHHHHHCCCCCC	7.83	-
891	Phosphorylation	DHYTEAYSRGRDSFS CCHHHHHHCCCCCCC	34.99	-
898	Phosphorylation	SRGRDSFSNSYGRSD HCCCCCCCCCCCCCC	28.90	28985074
900	Phosphorylation	GRDSFSNSYGRSDHY CCCCCCCCCCCCCCC	27.97	28985074
901	Phosphorylation	RDSFSNSYGRSDHYG CCCCCCCCCCCCCCC	22.32	-
907	Phosphorylation	SYGRSDHYGRGGCYE CCCCCCCCCCCCCCH	17.32	28985074
913	Phosphorylation	HYGRGGCYEEYQGRS CCCCCCCCHHHCCCC	18.31	-
916	Phosphorylation	RGGCYEEYQGRSPNA CCCCCHHHCCCCCCC	12.34	-
920	Phosphorylation	YEEYQGRSPNAYGGG CHHHCCCCCCCCCCC	29.36	-
924	Phosphorylation	QGRSPNAYGGGRGLN CCCCCCCCCCCCCCC	23.97	-
936	Phosphorylation	GLNSSNNSHGRSHRY CCCCCCCCCCCCCCC	31.41	-
943	Phosphorylation	SHGRSHRYGGGGRYE CCCCCCCCCCCCCCC	18.07	29978859
949	Phosphorylation	RYGGGGRYEEYRGPS CCCCCCCCCCCCCCC	19.18	29978859
952	Phosphorylation	GGGRYEEYRGPSPDA CCCCCCCCCCCCCCC	14.66	29978859
956	Phosphorylation	YEEYRGPSPDAHSGG CCCCCCCCCCCCCCC	37.93	29978859
1008	Phosphorylation	SSNSYGRSDRYSRGR CCCCCCCCCCCCCCC	23.29	29970186

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RMXL3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RMXL3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RMXL3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of RMXL3_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.