dbPTM

RLA0_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RLA0_RAT
UniProt AC	P19945
Protein Name	60S acidic ribosomal protein P0
Gene Name	Rplp0
Organism	Rattus norvegicus (Rat).
Sequence Length	317
Subcellular Localization	Nucleus . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein Description	Ribosomal protein P0 is the functional equivalent of E.coli protein L10..
Protein Sequence	MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPFSFGLIIQQVFDNGSIYSPEVLDITEQALHTRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFAAAAPVAAATTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MPREDRATWKSNYFL CCHHHHHHHHHHHHH	34.03	23984901
11	Phosphorylation	EDRATWKSNYFLKII HHHHHHHHHHHHHHH	28.46	23984901
24	Phosphorylation	IIQLLDDYPKCFIVG HHHHHHCCCCEEEEC	12.31	28432305
59	Phosphorylation	VVLMGKNTMMRKAIR EEEECCCHHHHHHHH	18.81	23984901
77	Acetylation	ENNPALEKLLPHIRG HCCHHHHHHHHHHCC	57.06	22902405
156	Phosphorylation	RGTIEILSDVQLIKT CCEEEECCCCEEEEC	41.20	30181290
273	Phosphorylation	KAFLADPSAFAAAAP HHHHCCHHHHHHHHH	36.24	28689409
285	Phosphorylation	AAPVAAATTAAPAAA HHHHHHHHCHHHHHH	16.55	22673903
286	Phosphorylation	APVAAATTAAPAAAA HHHHHHHCHHHHHHH	18.98	22673903
304	Phosphorylation	KVEAKEESEESDEDM EEEHHHHCCCCCCCC	47.99	23712012
307	Phosphorylation	AKEESEESDEDMGFG HHHHCCCCCCCCCCC	42.10	23712012

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RLA0_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RLA0_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RLA0_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of RLA0_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RLA0_RAT

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS."; Moser K., White F.M.; J. Proteome Res. 5:98-104(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-304 AND SER-307, ANDMASS SPECTROMETRY.	16396499 [Abstract]