RL7A_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL7A_MOUSE
• UniProt AC: P12970
• Protein Name: 60S ribosomal protein L7a
• Gene Name: Rpl7a
• Organism: Mus musculus (Mouse).
• Sequence Length: 266
• Protein Sequence: MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGHLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Ubiquitination	GKKAKGKKVAPAPAV CCCCCCCCCCCCCHH	52.91	-
11	Malonylation	GKKAKGKKVAPAPAV CCCCCCCCCCCCCHH	52.91	26320211
20	Ubiquitination	APAPAVVKKQEAKKV CCCCHHCCHHHHHHH	41.98	-
20	Malonylation	APAPAVVKKQEAKKV CCCCHHCCHHHHHHH	41.98	26320211
26	Ubiquitination	VKKQEAKKVVNPLFE CCHHHHHHHHCHHHH	59.47	-
26	Acetylation	VKKQEAKKVVNPLFE CCHHHHHHHHCHHHH	59.47	22826441
26	Malonylation	VKKQEAKKVVNPLFE CCHHHHHHHHCHHHH	59.47	26320211
34	Acetylation	VVNPLFEKRPKNFGI HHCHHHHHCCCCCCC	67.67	23864654
34	Ubiquitination	VVNPLFEKRPKNFGI HHCHHHHHCCCCCCC	67.67	-
34	Malonylation	VVNPLFEKRPKNFGI HHCHHHHHCCCCCCC	67.67	26320211
37	Ubiquitination	PLFEKRPKNFGIGQD HHHHHCCCCCCCCCC	69.78	-
37	Acetylation	PLFEKRPKNFGIGQD HHHHHCCCCCCCCCC	69.78	23864654
48	Ubiquitination	IGQDIQPKRDLTRFV CCCCCCCCCCHHHHC	42.01	-
48	Succinylation	IGQDIQPKRDLTRFV CCCCCCCCCCHHHHC	42.01	23806337
48	Acetylation	IGQDIQPKRDLTRFV CCCCCCCCCCHHHHC	42.01	23806337
75	Acetylation	AILYKRLKVPPAINQ HHHHHHCCCCHHHHH	57.64	22826441
75	Ubiquitination	AILYKRLKVPPAINQ HHHHHHCCCCHHHHH	57.64	-
97	Acetylation	QTATQLLKLAHKYRP HHHHHHHHHHHHHCC	52.82	23864654
97	Malonylation	QTATQLLKLAHKYRP HHHHHHHHHHHHHCC	52.82	26320211
97	Ubiquitination	QTATQLLKLAHKYRP HHHHHHHHHHHHHCC	52.82	-
101	Acetylation	QLLKLAHKYRPETKQ HHHHHHHHHCCCCHH	37.03	23864654
101	Ubiquitination	QLLKLAHKYRPETKQ HHHHHHHHHCCCCHH	37.03	-
125	Acetylation	AEKKAAGKGDVPTKR HHHHHCCCCCCCCCC	47.41	23806337
125	Malonylation	AEKKAAGKGDVPTKR HHHHHCCCCCCCCCC	47.41	26320211
125	Ubiquitination	AEKKAAGKGDVPTKR HHHHHCCCCCCCCCC	47.41	-
125	Succinylation	AEKKAAGKGDVPTKR HHHHHCCCCCCCCCC	47.41	23806337
131	Malonylation	GKGDVPTKRPPVLRA CCCCCCCCCCCCCCC	57.76	26320211
131	Acetylation	GKGDVPTKRPPVLRA CCCCCCCCCCCCCCC	57.76	23864654
131	Ubiquitination	GKGDVPTKRPPVLRA CCCCCCCCCCCCCCC	57.76	-
150	Succinylation	VTTLVENKKAQLVVI EHHHHCCCCEEEEEE	35.66	23806337
150	Acetylation	VTTLVENKKAQLVVI EHHHHCCCCEEEEEE	35.66	23864654
150	Ubiquitination	VTTLVENKKAQLVVI EHHHHCCCCEEEEEE	35.66	-
150	Malonylation	VTTLVENKKAQLVVI EHHHHCCCCEEEEEE	35.66	26320211
176	Ubiquitination	FLPALCRKMGVPYCI HHHHHHHHHCCCEEE	38.72	-
181	Phosphorylation	CRKMGVPYCIIKGKA HHHHCCCEEEEECCE	8.22	25367039
182	S-nitrosylation	RKMGVPYCIIKGKAR HHHCCCEEEEECCEE	1.81	21278135
182	S-palmitoylation	RKMGVPYCIIKGKAR HHHCCCEEEEECCEE	1.81	28526873
182	S-nitrosocysteine	RKMGVPYCIIKGKAR HHHCCCEEEEECCEE	1.81	-
199	S-nitrosylation	HLVHRKTCTTVAFTQ HHHCCCCCEEEEEEE	3.17	22178444
199	S-palmitoylation	HLVHRKTCTTVAFTQ HHHCCCCCEEEEEEE	3.17	28526873
199	S-nitrosocysteine	HLVHRKTCTTVAFTQ HHHCCCCCEEEEEEE	3.17	-
205	Phosphorylation	TCTTVAFTQVNSEDK CCEEEEEEECCCCCH	23.13	23984901
209	Phosphorylation	VAFTQVNSEDKGALA EEEEECCCCCHHHHH	48.60	25521595
212	Malonylation	TQVNSEDKGALAKLV EECCCCCHHHHHHHH	41.87	26320211
212	Acetylation	TQVNSEDKGALAKLV EECCCCCHHHHHHHH	41.87	23864654
212	Ubiquitination	TQVNSEDKGALAKLV EECCCCCHHHHHHHH	41.87	-
217	Acetylation	EDKGALAKLVEAIRT CCHHHHHHHHHHHHH	54.65	23864654
217	Ubiquitination	EDKGALAKLVEAIRT CCHHHHHHHHHHHHH	54.65	-
230	Phosphorylation	RTNYNDRYDEIRRHW HHCCHHHHHHHHHHC	22.31	-
245	Ubiquitination	GGNVLGPKSVARIAK CCCCCCHHHHHHHHH	56.62	-
246	Phosphorylation	GNVLGPKSVARIAKL CCCCCHHHHHHHHHH	24.92	23375375
259	Malonylation	KLEKAKAKELATKLG HHHHHHHHHHHHHHC	53.18	26320211

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL7A_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL7A_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL7A_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of RL7A_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.