UniProt ID | RL6_MOUSE | |
---|---|---|
UniProt AC | P47911 | |
Protein Name | 60S ribosomal protein L6 | |
Gene Name | Rpl6 | |
Organism | Mus musculus (Mouse). | |
Sequence Length | 296 | |
Subcellular Localization | Cytoplasm, cytosol . Cytoplasm . Rough endoplasmic reticulum . Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity). | |
Protein Description | Component of the large ribosomal subunit.. | |
Protein Sequence | MAGEKAPDTKEKKPAAKKAGSDAAASRPRAAKVAKKVHPKGKKPKKAKPHCSRNPVLVRGIGRYSRSAMYSRKALYKRKYSAAKTKVEKKKKKEKVLATVTKTVGGDKNGGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRRLRSSITPGTVLIILTGRHRGKRVVFLKQLDSGLLLVTGPLVINRVPLRRTHQKFVIATSTKVDISDVKIPKHLTDAYFKKKQLRKPRHQEGEIFDTEKEKYEITEQRKADQKAVDLQILPKIKAVPQLQGYLRSQFSLTNGMYPHKLVF | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
13 | Acetylation | APDTKEKKPAAKKAG CCCCCCCCHHHHHHC | 40.77 | 23201123 | |
18 | Ubiquitination | EKKPAAKKAGSDAAA CCCHHHHHHCCHHHH | 53.93 | - | |
21 | Phosphorylation | PAAKKAGSDAAASRP HHHHHHCCHHHHCCH | 29.01 | 26824392 | |
26 | Phosphorylation | AGSDAAASRPRAAKV HCCHHHHCCHHHHHH | 37.78 | 26824392 | |
51 | S-palmitoylation | PKKAKPHCSRNPVLV CCCCCCCCCCCCCCH | 5.76 | 26165157 | |
51 | Glutathionylation | PKKAKPHCSRNPVLV CCCCCCCCCCCCCCH | 5.76 | 24333276 | |
59 | Methylation | SRNPVLVRGIGRYSR CCCCCCHHCCCCCCH | 27.18 | 16188905 | |
65 | Phosphorylation | VRGIGRYSRSAMYSR HHCCCCCCHHHHHCH | 20.56 | 24719451 | |
80 | Phosphorylation | KALYKRKYSAAKTKV HHHHHHHHHHHHHHH | 13.94 | 23140645 | |
81 | Phosphorylation | ALYKRKYSAAKTKVE HHHHHHHHHHHHHHH | 25.45 | 23140645 | |
95 | Ubiquitination | EKKKKKEKVLATVTK HHHHHHHHEEEEEEE | 51.97 | - | |
95 | Malonylation | EKKKKKEKVLATVTK HHHHHHHHEEEEEEE | 51.97 | 26320211 | |
95 | Acetylation | EKKKKKEKVLATVTK HHHHHHHHEEEEEEE | 51.97 | 23201123 | |
102 | Ubiquitination | KVLATVTKTVGGDKN HEEEEEEEECCCCCC | 36.56 | - | |
102 | Acetylation | KVLATVTKTVGGDKN HEEEEEEEECCCCCC | 36.56 | 23806337 | |
102 | Malonylation | KVLATVTKTVGGDKN HEEEEEEEECCCCCC | 36.56 | 26320211 | |
102 | Succinylation | KVLATVTKTVGGDKN HEEEEEEEECCCCCC | 36.56 | 23806337 | |
108 | Ubiquitination | TKTVGGDKNGGTRVV EEECCCCCCCCEEEE | 61.85 | - | |
108 | Acetylation | TKTVGGDKNGGTRVV EEECCCCCCCCEEEE | 61.85 | 23201123 | |
123 | Phosphorylation | KLRKMPRYYPTEDVP EECCCCCCCCCCCCC | 14.13 | 26239621 | |
132 | Ubiquitination | PTEDVPRKLLSHGKK CCCCCCHHHHHCCCC | 47.94 | - | |
135 | Phosphorylation | DVPRKLLSHGKKPFS CCCHHHHHCCCCCHH | 40.40 | - | |
138 | Ubiquitination | RKLLSHGKKPFSQHV HHHHHCCCCCHHHHH | 52.42 | - | |
139 | Succinylation | KLLSHGKKPFSQHVR HHHHCCCCCHHHHHH | 56.75 | 23806337 | |
139 | Acetylation | KLLSHGKKPFSQHVR HHHHCCCCCHHHHHH | 56.75 | 23806337 | |
139 | Ubiquitination | KLLSHGKKPFSQHVR HHHHCCCCCHHHHHH | 56.75 | - | |
142 | Phosphorylation | SHGKKPFSQHVRRLR HCCCCCHHHHHHHHH | 28.09 | 24899341 | |
150 | Phosphorylation | QHVRRLRSSITPGTV HHHHHHHHCCCCCEE | 30.59 | 26824392 | |
151 | Phosphorylation | HVRRLRSSITPGTVL HHHHHHHCCCCCEEE | 24.85 | 26239621 | |
153 | Phosphorylation | RRLRSSITPGTVLII HHHHHCCCCCEEEEE | 20.01 | 26239621 | |
156 | Phosphorylation | RSSITPGTVLIILTG HHCCCCCEEEEEEEC | 17.22 | 26643407 | |
174 | Ubiquitination | GKRVVFLKQLDSGLL CEEEEEEEECCCCEE | 37.03 | - | |
200 | Acetylation | PLRRTHQKFVIATST CCCCCCCEEEEEECC | 33.71 | 22826441 | |
200 | Ubiquitination | PLRRTHQKFVIATST CCCCCCCEEEEEECC | 33.71 | - | |
208 | Ubiquitination | FVIATSTKVDISDVK EEEEECCCCCHHHCC | 37.36 | 22790023 | |
215 | Malonylation | KVDISDVKIPKHLTD CCCHHHCCCCHHHHH | 59.28 | 32601280 | |
215 | Acetylation | KVDISDVKIPKHLTD CCCHHHCCCCHHHHH | 59.28 | 23806337 | |
215 | Succinylation | KVDISDVKIPKHLTD CCCHHHCCCCHHHHH | 59.28 | 23806337 | |
215 | Ubiquitination | KVDISDVKIPKHLTD CCCHHHCCCCHHHHH | 59.28 | - | |
218 | Malonylation | ISDVKIPKHLTDAYF HHHCCCCHHHHHHHH | 55.51 | 32601280 | |
218 | Ubiquitination | ISDVKIPKHLTDAYF HHHCCCCHHHHHHHH | 55.51 | 22790023 | |
218 | Acetylation | ISDVKIPKHLTDAYF HHHCCCCHHHHHHHH | 55.51 | 22826441 | |
224 | Phosphorylation | PKHLTDAYFKKKQLR CHHHHHHHHHHHHCC | 20.81 | 29514104 | |
226 | Succinylation | HLTDAYFKKKQLRKP HHHHHHHHHHHCCCC | 46.51 | 23954790 | |
226 | Ubiquitination | HLTDAYFKKKQLRKP HHHHHHHHHHHCCCC | 46.51 | - | |
226 | Acetylation | HLTDAYFKKKQLRKP HHHHHHHHHHHCCCC | 46.51 | 22826441 | |
243 | Phosphorylation | QEGEIFDTEKEKYEI CCCCCCCCHHHHEEC | 37.90 | 26525534 | |
245 | Acetylation | GEIFDTEKEKYEITE CCCCCCHHHHEECCH | 62.69 | 23864654 | |
245 | Ubiquitination | GEIFDTEKEKYEITE CCCCCCHHHHEECCH | 62.69 | 22790023 | |
247 | Acetylation | IFDTEKEKYEITEQR CCCCHHHHEECCHHH | 60.29 | 23806337 | |
247 | Ubiquitination | IFDTEKEKYEITEQR CCCCHHHHEECCHHH | 60.29 | - | |
255 | Ubiquitination | YEITEQRKADQKAVD EECCHHHHHHHHHHH | 56.88 | - | |
259 | Succinylation | EQRKADQKAVDLQIL HHHHHHHHHHHCHHH | 51.42 | 23954790 | |
259 | Acetylation | EQRKADQKAVDLQIL HHHHHHHHHHHCHHH | 51.42 | 23864654 | |
259 | Ubiquitination | EQRKADQKAVDLQIL HHHHHHHHHHHCHHH | 51.42 | - | |
268 | Succinylation | VDLQILPKIKAVPQL HHCHHHHHHCCHHHH | 54.09 | 23806337 | |
268 | Acetylation | VDLQILPKIKAVPQL HHCHHHHHHCCHHHH | 54.09 | 23806337 | |
270 | Ubiquitination | LQILPKIKAVPQLQG CHHHHHHCCHHHHHH | 49.83 | 22790023 | |
281 | Phosphorylation | QLQGYLRSQFSLTNG HHHHHHHHHHCCCCC | 32.74 | 29514104 | |
284 | Phosphorylation | GYLRSQFSLTNGMYP HHHHHHHCCCCCCCC | 27.01 | 29514104 | |
293 | Ubiquitination | TNGMYPHKLVF---- CCCCCCCCCCC---- | 41.67 | 22790023 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RL6_MOUSE !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RL6_MOUSE !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RL6_MOUSE !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
Oops, there are no PPI records of RL6_MOUSE !! |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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