dbPTM

RL4_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RL4_DROME
UniProt AC	P09180
Protein Name	60S ribosomal protein L4
Gene Name	RpL4
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	401
Subcellular Localization
Protein Description
Protein Sequence	MSLGNARPLVSVYTEKNEPAKDKNICLPAVFKAPIRPDVVNEVHQLLRRNNRQAYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTFRRWHRKVNVNQRRYALVSAIAASGVPALVQSKGHVIDGVSEFPLVVSDEVQKVQKTKQAVIFLRRLKIWADIQKVYKSQRFRAGRGTMRDRRRIARRGPLVVYDKDEGLRKAFRNIPGIETINVDKLNLLKLAPGGHVGRFVIWTESAFARLNDLFGTWKKPSTLKKGYNLPQPKMANTDLSRLLKSEEIRKVLRDPRKRVFRSVRRLNPLTNVRQLIKLNPYAEVLKRRAALAAEKRTVAKVLAKAKKQNVELAKSHFANVATKAAANRAKLLAARKKKVAAKKPAAKK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSLGNARPL ------CCCCCCCCC	45.01	27794539
16	Acetylation	LVSVYTEKNEPAKDK CEEEEECCCCCCCCC	59.83	21791702
109	Acetylation	GRMFAPTKTFRRWHR CCCCCCCHHHHHHHH	44.61	21791702
129	Phosphorylation	QRRYALVSAIAASGV HHHHHHHHHHHHCCC	18.14	22817900
134	Phosphorylation	LVSAIAASGVPALVQ HHHHHHHCCCCHHHH	31.16	22817900
158	Phosphorylation	SEFPLVVSDEVQKVQ CCCCEEECHHHHHHH	22.15	22817900
216	Acetylation	GPLVVYDKDEGLRKA CCEEEEECCHHHHHH	39.74	21791702
297	Acetylation	TDLSRLLKSEEIRKV CHHHHHHCHHHHHHH	61.48	21791702
330	Ubiquitination	TNVRQLIKLNPYAEV CCHHHHHHHCHHHHH	51.29	31113955

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RL4_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RL4_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RL4_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ATRIP_DROME	mus304	physical	14605208

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RL4_DROME

Related Literatures of Post-Translational Modification